Extensive epidemiological research links early-life exposures with adult non-communicable diseases. Studying these "Developmental Origins of Health and Disease" (DOHaD), and the underlying mechanisms, can be challenging given that the duration of time between exposure and clinical outcome can be a number of decades. As such, the use of pre-clinical markers of disease progression, and the mechanisms driving such, is attractive and frequently warranted, as surrogate outcomes in cohorts and randomised trials.
This meeting will provide an evidence-based perspective of the key methodologies for assessing cardiac, vascular, metabolic and immune health within the paradigm of life course research. The content will be of particular relevance to life course researchers currently undertaking, or looking to undertake, randomized trials, cohort studies or other clinical research, and looking to incorporate evidence-based assessment of cardiac and vascular health, metabolic health, adiposity and immune health.
There will be a particular focus on state-of-the-art and gold standard methodologies for each of the key stages in life course research – fetus, infant, child, adolescent, and adult, with the latter including preconception, pregnancy, and postpartum. Cost-effective alternatives will also be covered, and those methodologies that can be applied in the field, including in remote communities.
This meeting will also feature a live demonstration of key methodologies, and a hands-on workshop introducing Healthy Conversations.
Download the program (PDF, 308KB)