A unit of study with lectures, practicals and tutorials on the application of recombinant DNA technology and the genetic manipulation of prokaryotic and eukaryotic organisms. Lectures cover the applications of molecular genetics in biotechnology and consider the regulation, impact and implications of genetic engineering and genomics. Topics include biological sequence data and databases, comparative genomics, the cloning and expression of foreign genes in bacteria, yeast, animal and plant cells, novel human and animal therapeutics and vaccines, new diagnostic techniques for human and veterinary disease, and the genetic engineering of animals and plants. Practical work may include nucleic acid isolation and manipulation, gene cloning and PCR amplification, DNA sequencing and bioinformatics, immunological detection of proteins, and the genetic transformation and assay of plants.
Two 1-hour lectures and one 3-hour practical per week.
One 2-hour exam (60%), assignments (40%).
(MBLG2X72 or GEGE2X01 or GENE2002) and 6cp from (MBLG2X71 or BCMB2XXX or QBIO2001 or IMMU2XXX or BIOL2XXX or MEDS2003)Prohibitions