Major changes to the way we discover and develop new medicines have taken place in recent years. Sequencing of the human genome has revolutionised drug target identification and therapeutic design. Approaches that combine molecular biology and intensive data analysis are key to the development of effective personalised and precision therapies. New methods in organic synthesis have accelerated how we explore chemical space and parallel developments in nanotechnology are driving innovative drug delivery methods. Improvements in cell, tissue and animal models of human disease are changing how drugs are identified and tested. In this unit, you will explore how these new ideas and technologies are transforming medicinal chemistry. You will learn and apply such techniques to the molecular-level understanding of diseases and the design of effective therapeutics. You will learn the procedures leading to drug registration and regulation. You will participate in enquiry-led practicals that reinforce the concepts of the unit and develop your skills in cutting-edge methods used in modern medicinal chemistry. By studying this unit you will build knowledge and skills that will enable you to play a role in creating therapeutics that will impact lives.
lecture 2 hrs/week
2 x in-class test (10%), oral presentation (10%), 2 x group workshop (20%), lab report (20%), final exam (40%)
[(PCOL2011 or PCOL2021 or MEDS2002) or (BMED2401 and BMED2402) or (BMED2401 and BMED2405)] or (12cp from BCMB2XXX) and [(CHEM2401 or CHEM2521 or CHEM2911 or CHEM2915 or CHEM2921 or CHEM2991)]Prohibitions