This unit of study aims to provide knowledge on the role of micro-organisms in pharmacy and the pharmaceutical sciences. It applies basic microbiological principles to the production of clean and sterile pharmaceutical products in both community and hospital pharmacy, and in industrial manufacture, and antimicrobial therapies. Topics include the structure, function and importance of the major groups of micro-organisms; host defence mechanisms; pathogenicity and epidemiology of infectious diseases; disinfectants; preservatives; antiseptics; antibiotics, antibiotic resistance, and antimicrobial stewardship; principles and methods of sterilisation, aseptic preparation and techniques; cleanroom technology and good manufacturing practice (GMP).
1x2hr lecture/week, 1x3hr practicals (3 weeks), 1x3hr workshop (3 weeks)
1.5hr final exam (60%), microbiology lab attendance and participation (2%), microbiology lab report (5%), online quizzes and pre-lab tasks (8%), antibiotic resistance workshop presentation (15%), antibiotic stewardship workshop assignment (10%)
Recommended Texts: Denyer S., Stephen P. (2011). Hugo And Russell's Pharmaceutical Microbiology (8th ed) Chichester, West Sussex, UK: Wiley-Blackwell Russell, A. D., Hugo, W. B., Ayliffe, G. A. J., Fraise, A.P., Lambert, P.A., and Maillard, J.Y. (2013). Russell, Hugo and Ayliffe's principles and practice of disinfection, preservation and sterilization (5th ed) Chichester: Wiley-Blackwell Tortora, G.J., Funke, B.R., Case, C.L. (2016). Microbiology: An Introduction (12th ed) Boston: Pearson Anderson, R. (2012). Antibacterial Agents: Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications. Oxford: Wiley-Blackwell Willig, S.H. (2001) Good manufacturing practices for pharmaceuticals: a plan for total quality control from manufacturer to consumer (5th ed) New York: Marcel Dekker
6 credit points of Biochemistry, 12 credit points of Chemistry, 12 credit points of Pharmacology, 12 credit points of Physiology.