University of Sydney Handbooks - 2021 Archive

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Immunology and Pathology

Unit outlines will be available through Find a unit outline two weeks before the first day of teaching for 1000-level and 5000-level units, or one week before the first day of teaching for all other units.
 

IMMUNOLOGY AND PATHOLOGY

Immunology and Pathology major

A major in Immunology and Pathology requires 48 credit points from this table including:
(i) 12 credit points of 1000-level core units
(ii) 6 credit points of 2000-level core units
(iii) 6 credit points of 2000-level core units according to the following:
(a) 6 credit points of 2000-level MIMI coded units or
(b) 6 credit points of 2000-level MEDS coded units for students in the Medical Science stream
(iv) 12 credit points of 3000-level core units
(v) 6 credit points of 3000-level selective units
(vi) 6 credit points of 3000-level interdisciplinary project units

Units of study

The units of study are listed below.

1000-level units of study

Core
BIOL1007 From Molecules to Ecosystems

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive February,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: BIOL1907 or BIOL1997 Assumed knowledge: HSC Biology. Students who have not completed HSC Biology (or equivalent) are strongly advised to take the Biology Bridging Course (offered in February). Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Block mode
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . You will participate in inquiry-led practicals that reinforce the concepts in the unit. By doing this unit you will develop knowledge and skills that will enable you to play a role in finding global solutions that will impact our lives.
BIOL1907 From Molecules to Ecosystems (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: BIOL1007 or BIOL1997 Assumed knowledge: 85 or above in HSC Biology or equivalent Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and discover how expanding tools have improved our capacity to manage and intervene in ecosystems for our own health and organisms in the environment that surround and support us . This unit of study has the same overall structure as BIOL1007 but material is discussed in greater detail and at a more advanced level. The content and nature of these components may vary from year to year.
Textbooks
Please see unit outline on LMS
BIOL1997 From Molecules to Ecosystems (SSP)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: BIOL1007 or BIOL1907 Assumed knowledge: 90 or above in HSC Biology or equivalent Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Paradigm shifts in biology have changed the emphasis from single biomolecule studies to complex systems of biomolecules, cells and their interrelationships in ecosystems of life. Such an integrated understanding of cells, biomolecules and ecosystems is key to innovations in biology. Life relies on organisation, communication, responsiveness and regulation at every level. Understanding biological mechanisms, improving human health and addressing the impact of human activity are the great challenges of the 21st century. This unit will investigate life at levels ranging from cells, and biomolecule ecosystems, through to complex natural and human ecosystems. You will explore the importance of homeostasis in health and the triggers that lead to disease and death. You will learn the methods of cellular, biomolecular, microbial and ecological investigation that allow us to understand life and intervene in ecosystems to improve health. The same theory will be covered as in the advanced stream but in this Special Studies Unit, the practical component is a research project. The research will be a synthetic biology project investigating genetically engineered organisms. Students will have the opportunity to develop higher level generic skills in computing, communication, critical analysis, problem solving, data analysis and experimental design.
Textbooks
Please see unit outline on LMS
CHEM1011 Fundamentals of Chemistry 1A

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1111 or CHEM1911 or CHEM1991 Assumed knowledge: There is no assumed knowledge of chemistry for this unit of study but students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February). Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February, and online year-round, see https://sydney.edu.au/students/bridging-courses.html).
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will equip you with the fundamental knowledge and skills in chemistry for broad application. You will learn about atomic theory, structure and bonding, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students whose chemical background is weak (or non-existent). Compared to the mainstream Chemistry 1A, the theory component of this unit begins with more fundamental concepts, and does not cover, or goes into less detail about some topics. Progression to intermediate chemistry from this unit and Fundamentals of Chemistry 1B requires completion of an online supplementary course.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1111 Chemistry 1A

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive February,Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1911 or CHEM1991 Assumed knowledge: Students who have not completed HSC Chemistry (or equivalent) and HSC Mathematics (or equivalent) are strongly advised to take the Chemistry and Mathematics Bridging Courses (offered in February) Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students who have not completed secondary school chemistry are strongly advised to instead complete Fundamentals of Chemistry 1A in the first semester of the calendar year (unless you require 12 credit points of Chemistry and are commencing in semester 2). You should also take the Chemistry Bridging Course in advance (offered in February, and online year-round https://sydney.edu.au/students/bridging-courses.html).
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions like how do dyes work, how do we desalinate water, how do we measure the acid content in foods, how do we get the blue in a blueprint, and how do we extract natural products from plants? Through inquiry, observation and measurement, you will understand the 'why' and the 'how' of the natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a satisfactory prior knowledge of the HSC chemistry course.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1911 Chemistry 1A (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1991 Assumed knowledge: 80 or above in HSC Chemistry or equivalent Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for broad application, including further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a good secondary performance both overall and in chemistry or science. Students in this category are expected to do this unit rather than Chemistry 1A. Compared to the mainstream Chemistry 1A, the theory component of this unit provides a higher level of academic rigour and makes broader connections between topics.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1991 Chemistry 1A (Special Studies Program)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1911 Assumed knowledge: 90 or above in HSC Chemistry or equivalent Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry in small group projects. The laboratory program is designed to extend students who already have chemistry laboratory experience, and particularly caters for students who already show a passion and enthusiasm for research chemistry, as well as aptitude as demonstrated by high school chemistry results. Entry to Chemistry 1A (Special Studies Program) is restricted to a small number of students with an excellent school record in Chemistry, and applications must be made to the School of Chemistry. The practical work syllabus for Chemistry 1A (Special Studies Program) is very different from that for Chemistry 1A and Chemistry 1A (Advanced) and consists of special project-based laboratory exercises. All other unit of study details are the same as those for Chemistry 1A (Advanced).
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
MEDS coded units of study are only available to students in the Medical Science stream.

2000-level units of study

Core
IMMU2011 Immunobiology

Credit points: 6 Teacher/Coordinator: Dr Umaimainthan Palendira Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1 Prohibitions: IMMU2911 Assumed knowledge: CHEM1XX1 or CHEM1903 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses mounted by animals, both vertebrates and invertebrates, plants and microbes themselves. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combatting infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as the development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with an overview of immunobiology as a basic research science. We will explore the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Practical and tutorial sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. Upon completion, you will have developed the foundations to undertake further studies in Biology, Animal Health, Immunology and Pathology. Ultimately, this could lead you to a career in medical research, biosecurity and/or Veterinary Science.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
IMMU2911 Immunobiology (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Umaimainthan Palendira Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 70 or above in [BIOL1XX7 or (BIOL1XX8 or BIOL1XX3 or MEDS1X01) or BIOL1XX2 or MBLG1XX1] Prohibitions: IMMU2011 Assumed knowledge: CHEM1XX1 or CHEM1903 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
Immunobiology is the study of defence mechanisms that protect living organisms against life-threatening infections. In this unit of study you will explore the essential features of the host immune responses and how it evolved from unicellular organisms to complex multi-cellular organisms. Studies in animal and microbial immunobiology are leading to breakthroughs in veterinary and clinical medicine, including combatting infectious diseases, maximising transplant success, treating allergies, autoimmune diseases and cancer, as well as development of new vaccines to prevent disease. Understanding the immunobiology of plants also enables us to protect crops from disease which enhances our food security. In this unit of study you will be provided with a detailed overview of immunobiology as a basic research science. We will explore in detail the nature of the immune cells and molecules that recognise danger and how the immune system of animals and plants respond at the cellular and molecular level. Advanced practical and tutorial sessions are designed to illustrate particular concepts introduced in other face-to-face activities. Further self-directed learning activities, including online learning activities, will facilitate integration of fundamental information and help you apply this knowledge to the ways in which the host organism defends against disease. This advanced version of Immunobiology has the same overall concepts as the mainstream unit but material is discussed in a manner that offers a greater level of challenge and academic rigour. Students enrolled in the advanced stream will participate in alternative components which may for example include guest lectures from experts. The nature of these components may vary from year to year.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
MIMI coded core
MIMI2002 Microbes, Infection and Immunity

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: (BIOL1XX7 or MBLG1XX1 or BIOL1XX8 or MEDS1X01 or BIOL1XX3) Prohibitions: MEDS2004 or BMED2404 or MIMI2902 or IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit of study you will establish a conceptual foundation and, using an integrated approach, explore selected case studies of infection from a body system of origin perspective. You will explore the characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and characteristic pathological changes to tissue that arise will then be considered. Upon completion of this unit, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways in which your immune system recognises and destroys invading microbes; how T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. You will develop a holistic perspective of infectious diseases. You will work collaboratively to solve challenging problems in Biomedical Sciences. Practical classes will investigate normal flora, host defences and case studies of medically important microbes with linkage to disease outcome. You will also obtain experience and understanding of modern experimental techniques in microbiology and immunopathology.
Textbooks
Willey, J., Sherwood, L., Woolverton, C., Prescott, L., 2017, Prescott's Microbiology, 10th Edition. McGraw-Hill Australia Pty Ltd, Sydney.
MIMI2902 Microbes, Infection and Immunity (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 70 or above in (BIOL1XX7 or MBLG1XX1 or BIOL1XX8 or MEDS1X01 or BIOL1XX3) Prohibitions: MEDS2004 or BMED2404 or MIMI2002 or IMMU2101 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit you will establish a conceptual foundation and, using an integrated approach, explore selected infection case studies from a body system of origin perspective. You will explore characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and consequent characteristic pathological changes to tissue will be considered. Upon completion, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways your immune system recognises and destroys invading microbes; how T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. This advanced unit has the same overall structure as MIMI2002 but contains a unique science communication exercise in which you will actively participate in small group sessions and be assessed with a short essay. This advanced component explores how recent advances in microbiology, infection and immunity are communicated to the wider public and is based on recent publications with potential high impact for society.
MEDS coded core
MEDS2004 Microbes, Infection and Immunity

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: BIOL1XX3 or BIOL1XX7 or BIOL1X08 or MEDS1X01 or MBLG1XX1 Prohibitions: MIMI2002 or MIMI2902 or MICR2021 or MICR2921 or MICR2022 or MICR2922 or IMMU2101 or BMED2404 or BMED2807 or BMED2808 Assumed knowledge: Human biology (BIOL1XX3 or BIOL1XX8 or MEDS1X01) and biological chemistry (CHEM1XX1 or CHEM1903) Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Transmission, pathogenicity and immune response to microbes are key concepts for understanding infectious disease processes. In this unit of study you will establish a conceptual foundation and, using an integrated approach, explore selected case studies of infection from a body system of origin perspective. You will explore the characteristics of viral, bacterial, fungal and protist pathogens and their virulence mechanisms for establishment and progression of disease. Comprehensive consideration of host immune response and characteristic pathological changes to tissue that arise will then be considered. Upon completion of this unit, you will be able to explain microbial pathogenic processes of infection including: mechanisms for colonisation, invasion and damage to host tissue; the ways in which your immune system recognises and destroys invading microbes; how the T cell response is activated and antibodies function. You will learn about pathogenesis, symptoms, current challenges of treatment including antibiotic resistance, control and vaccination strategies. You will develop a holistic perspective of infectious diseases. You will work collaboratively to solve challenging problems in Biomedical Sciences. Practical classes will investigate normal flora, host defences and case studies of medically important microbes with linkage to disease outcome. You will also obtain experience and understanding of modern experimental techniques in microbiology and immunopathology.
Textbooks
Learning resources will be available via the course Canvas site. Recommended textbooks: Willey, J., Sherwood, L., Woolverton, C., Prescott, L., 2017, Prescott's Microbiology, 10th Edition. McGraw-Hill Australia Pty Ltd, Sydney and Abbas, A., Lichtman, A., Pillai, S. 2016, Basic Immunology: Functions and disorders of the immune system, 5th Edition. Elsevier St. Louis, Missouri, USA.
(MEDS coded units of study are only available to students in the Medical Science stream).

3000-level units of study

Core
CPAT3201 Pathogenesis of Human Disease 1

Credit points: 6 Teacher/Coordinator: A/Prof Paul Witting Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 6CP of (IMMU2X11 or MEDS2004 or MIMI2X02 or IMMU2101 or BMED2404) Prohibitions: CPAT3901 Assumed knowledge: Sound knowledge of biology through meeting pre-requisites Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
The Pathogenesis of Human Disease 1 unit of study modules will provide a theoretical background to the scientific basis of the pathogenesis of disease. Areas covered in theoretical modules include: tissue responses to exogenous factors, adaptive responses to foreign agents, cardiovascular/pulmonary/gut responses to disease, forensic science, neuropathology and cancer. The aims of the course are: - To give students an overall understanding of the fundamental biological mechanisms governing disease pathogenesis in human beings. - To introduce to students basic concepts of the pathogenesis, natural history and complications of common human diseases. - To demonstrate and exemplify differences between normality and disease. - To explain cellular aspects of certain pathological processes. Together with CPAT3202, the unit of study would be appropriate for those who intend to proceed to Honours research, to postgraduate studies such as Medicine or to careers in biomedical areas such as hospital science. Enquires should be directed to anthea.matsimanis@sydney.edu.au
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CPAT3901 Pathogenesis of Human Disease 1 (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Paul Witting Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 6CP of (IMMU2X11 or MEDS2004 or MIMI2X02 or IMMU2101 or BMED2404) Prohibitions: CPAT3201 Assumed knowledge: A working knowledge of biology Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day, Block mode
Note: Department permission required for enrolment
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
A deep understanding of pathological mechanisms for disease progression leads to improved human health outcomes. As human populations across the world are ageing, the increasing burden of age-related disease will become one of the greatest challenges facing modern medical science. To equip students with skills appropriate for job-ready careers in the biomedical sciences specialising in pathology it is necessary to provide an integrated understanding of how to evaluate and analyse crucial pathological mechanisms governing disease progression in humans. You will participate in inquiry-led learning modules focused on the systems theory of disease and the underlying mechanisms that promote disease progression in humans. To demonstrate disease you will review high-resolution imagery of pathological specimens using innovative online tools combined with in-depth description of immunological, molecular and biochemical process that underpin the pathogenesis of disease in a range of major body organs. You will undertake investigations to gain an advanced understanding of the health complications of common human diseases. You will learn to use a process of high-level deduction to identify key differences between normality and disease in order to explain cellular aspects of certain pathological processes. Through undertaking this unit you will develop the necessary skill set to define and strategically assess how different organ systems react to injury/insult and how to apply basic concepts of disease processes, which ultimately improve the capacity to manage and intervene in fundamental and clinical aspects of health and disease.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
IMMU3102 Molecular and Cellular Immunology

Credit points: 6 Teacher/Coordinator: A/Prof Carl Feng Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11 Prohibitions: IMMU3902 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This study unit builds on the series of lectures that outlined the general properties of the immune system, effector lymphocytes and their functions, delivered in the core courses IMMU2X11 Immunobiology and MIMI2X02/MEDS2004 Microbes, Infection and Immunity, IMMU2101 ­ Introductory Immunology and BMED2404 ­ Microbes, Infection and Immunity (formerly IMMU2001 and BMED2807). In this unit the molecular and cellular aspects of the immune system are investigated in detail. We emphasise fundamental concepts to provide a scientific basis for studies of the coordinated and regulated immune responses that lead to elimination of infectious organisms. Guest lectures from research scientists eminent in particular branches of immunological research are a special feature of the course. These provide challenging information from the forefront of research that will enable the student to become aware of the many components that come under the broad heading 'Immunology'.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
IMMU3902 Molecular and Cellular Immunology (Advanced)

Credit points: 6 Teacher/Coordinator: A/Prof Carl Feng Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 70 or above in (IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11) Prohibitions: IMMU3102 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This unit is available to students who have performed well in Introductory Immunology (IMMU2101) IMMU2X11 Immunobiology or MIMI2X02/MEDS2004 Microbes, Infection and Immunity. Advanced students will complete the same core lecture material as students in IMMU3102 but attend a series of specialized seminar and research based tutorial classes.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
Selective
CPAT3202 Pathogenesis of Human Disease 2

Credit points: 6 Teacher/Coordinator: Dr Melanie White Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 6cp from CPAT3201 or CPAT3901 Corequisites: CPAT3201 Prohibitions: CPAT3902 Assumed knowledge: Sound knowledge of biology through meeting pre-requisites Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
The Pathogenesis of Human Disease 2 unit of study modules will provide a theoretical and practical background to the scientific basis of the pathogenesis of systemic diseases. Extending upon the knowledge gained from CPAT3201, areas covered in practical modules include the response of renal, gut, cardiovascular, neurological and gynaecological systems to disease. In the practical modules, these areas will be expanded to include specimen evaluation on a macroscopic and microscopic basis. The aims of the course are: ­ To enable students to gain an understanding of how different organ systems react to injury and to apply basic concepts of disease processes. ­ To equip students with skills appropriate for careers in the biomedical sciences and for further training in research or professional degrees. At the end of the course students will: ­ Have the ability to describe, synthesise and present information on disease pathogenesis. ­ Transfer problem­solving skills to novel situations related to disease pathogenesis. Have acquired practical skills in the use of a light microscope. ­ Have an understanding of basic investigative techniques for disease detection in pathology. ­ Be able to evaluate diseased tissue at the macroscopic and microscopic level. ­ Have the ability to describe, synthesise and present information on disease pathogenesis. ­ Transfer problem­solving skills to novel situations related to disease pathogenesis. This unit of study would be appropriate for those who intend to proceed to Honours research, to postgraduate studies such as Medicine or to careers in biomedical areas such as hospital science. Enquiries should be directed to soms.education@sydney.edu.au
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CPAT3902 Pathogenesis of Human Disease 2 (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Melanie White Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 70 or above in 6CP from CPAT3201 or CPAT3901 Prohibitions: CPAT3202 Assumed knowledge: A working knowledge of biology Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
Understanding the underlying mechanisms of disease and disease progression, improving human health and addressing the impact of human activity on individual health outcomes are some of the great challenges facing modern medical sciences in the 21st century. To equip students with skills appropriate for careers in the biomedical sciences and for further training in research or professional degrees it is necessary to provide an integrated understanding of how to evaluate and analyse crucial pathological mechanisms governing disease progression in humans. You will participate in inquiry-led museum and practical class sessions that review human pathological specimens using innovative online tools combined with high-resolution microscopy to crystallise and reinforce concepts developed in the unit. You will undertake investigations to gain an advanced understanding of the pathogenesis, natural history and related health complications of common human diseases. You will learn to use methodologies to exemplify key differences between normality and disease in order to explain cellular aspects of certain pathological processes. Through undertaking this unit you will develop the necessary practical skills required to employ advanced imaging technologies that are increasingly used to define and strategically assess how different organ systems react to injury/insult, which ultimately improve the capacity to manage and intervene in fundamental and clinical aspects of health and disease.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
IMMU3202 Immunology in Human Disease

Credit points: 6 Teacher/Coordinator: Prof Allison Abendroth Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11 Prohibitions: IMMU3903 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This study unit builds on the series of lectures that outlined the general properties of the immune system, effector lymphocytes and their functions, delivered in the core courses , IMMU2101 ­ Introductory Immunology and BMED2404 ­ Microbes, Infection and Immunity (formerly IMMU2001 and BMED2807) IMMU2X11 Immunobiology and MIMI2X02/MEDS2004 Microbes, Infection and Immunity. We emphasise fundamental concepts to provide a scientific basis for studies in clinical immunology; dysfunctions of the immune system e.g. autoimmune disease, immunodeficiencies, and allergy, and immunity in terms of host ­ pathogen interactions. This unit has a strong focus on significant clinical problems in immunology and the scientific background to these problems. The unit includes lectures from research scientists and clinicians covering areas such as allergy, immunodeficiency, autoimmune disease and transplantation. This course provides challenging information from the forefront of clinical immunology and helps the student develop an understanding of immune responses in human health and disease. Three lectures (1 hour each) will be given each fortnight: 2 lectures in one week and one lecture the following week, for the duration of the course. This unit directly complements the unit 'Molecular and Cellular Immunology IMMU3102' and students are very strongly advised to undertake these study units concurrently.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
IMMU3903 Immunology in Human Disease (Advanced)

Credit points: 6 Teacher/Coordinator: Prof Allison Abendroth Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 70 or above in (IMMU2101 or BMED2404 or MEDS2004 or MIMI2X02 or IMMU2X11) Prohibitions: IMMU3202 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This unit is available to students who have performed well in Introductory Immunology (IMMU2101) IMMU2X11 Immunobiology and MIMI2X02/MEDS2004 Microbes, Infection and Immunity. Advanced students will complete the same core lecture material as students in IMMU3202 but attend a series of specialized seminar and research based tutorial classes.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
Interdisciplinary Project
IMPA3888 Immunopathology Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: MEDS2004 or MIMI2X02 or IMMU2101 or BMED2404 or IMMU2X11 Assumed knowledge: Fundamental cellular and molecular immunology and pathology as taught in IMMU3102 and CPAT3201 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
This unit expands on your disciplinary knowledge in Immunology and Pathology by viewing it in the context of real-world health problems. The major aim of the unit is to work with students from other areas of science and medical science to understand that disease is not purely a host versus disease paradigm but integrates human behaviour, culture, economics, history and geography. Depending on the disease, these factors may be as important as the pathogen itself in defining our approach to treatments. Moreover, in chronic diseases such as type 2 diabetes or complex disorders such as depression societal factors can be the sole or major aetiological agent in the absence of a pathogen altogether. This unit will introduce to you through a series of expert panel discussions and workshops knowledge of other perspectives of disease including perceived and inadvertent biases that can affect design and interpretation of experimental results. Once empowered with this wider understanding of disease we will challenge you individually, and as part of your interdisciplinary team to define and solve a complex health problem of your choice. Your group will produce consultation paper that directs policy and investment towards the area that you consider most likely to reduce the burden of your chosen disease. Your report will also be summarised in the form of a poster and oral presentation and be reviewed by Academics and your peers.
Textbooks
Learning resources will be available via the course Canvas site. Recommended Textbooks: 1. Abbas, Lichtman and Pillai. Cellular and Molecular Immunology. 9th Edition. 2017. 2. Kumar, Abbas and Aster. Robbins Basic Pathology, 9th edition. 2012.
SCPU3001 Science Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive February,Intensive July,Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 96 credit points Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
This interdisciplinary unit provides students with the opportunity to address complex problems identified by industry, community, and government organisations, and gain valuable experience in working across disciplinary boundaries. In collaboration with a major industry partner and an academic lead, students integrate their academic skills and knowledge by working in teams with students from a range of disciplinary backgrounds. This experience allows students to research, analyse and present solutions to a real¿world problem, and to build on their interpersonal and transferable skills by engaging with and learning from industry experts and presenting their ideas and solutions to the industry partner.