Medicinal Chemistry Descriptions

Unit outlines will be available through Find a unit outline two weeks before the first day of teaching for 1000-level and 5000-level units, or one week before the first day of teaching for all other units.
 

MEDICINAL CHEMISTRY

Medicinal Chemistry major

A major in Medicinal Chemistry requires 48 credit points from this table including:
(i) 12 credit points of 1000-level core units
(ii) 6 credit points of 2000-level core units
(iii) 6 credit points of pharmacology units according to the following:
(a) 6 credit points of 2000-level PCOL coded units or
(b) 6 credit points of 2000-level MEDS coded pharmacology units for students in the Medical Science Stream
(iv) 12 credit points of 3000-level major core units
(v) 6 credit points of 3000-level chemistry selective units
(vi) 6 credit points of 3000-level interdisciplinary project units

Medicinal Chemistry minor

A minor in Medicinal Chemistry requires 36 credit points from this table including:
(i) 12 credit points 1000-level core units
(ii) 6 credit points of 2000-level core units
(iii) 6 credit points of pharmacology units according to the following:
(a) 6 credit points of 2000-level PCOL coded units or
(b) 6 credit points of 2000-level MEDS coded pharmacology units for students in the Medical Science stream
(iv) 6 credit points of 3000-level minor core units
(v) 6 credit points of 3000-level minor selective units

Units of study

The units of study are listed below.

1000-level units of study

Core
CHEM1011 Fundamentals of Chemistry 1A

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1111 or CHEM1911 or CHEM1991 Assumed knowledge: There is no assumed knowledge of chemistry for this unit of study but students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February). Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students who have not completed HSC Chemistry (or equivalent) are strongly advised to take the Chemistry Bridging Course (offered in February, and online year-round, see https://sydney.edu.au/students/bridging-courses.html).
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will equip you with the fundamental knowledge and skills in chemistry for broad application. You will learn about atomic theory, structure and bonding, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students whose chemical background is weak (or non-existent). Compared to the mainstream Chemistry 1A, the theory component of this unit begins with more fundamental concepts, and does not cover, or goes into less detail about some topics. Progression to intermediate chemistry from this unit and Fundamentals of Chemistry 1B requires completion of an online supplementary course.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1111 Chemistry 1A

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive February,Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1911 or CHEM1991 Assumed knowledge: Students who have not completed HSC Chemistry (or equivalent) and HSC Mathematics (or equivalent) are strongly advised to take the Chemistry and Mathematics Bridging Courses (offered in February) Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students who have not completed secondary school chemistry are strongly advised to instead complete Fundamentals of Chemistry 1A in the first semester of the calendar year (unless you require 12 credit points of Chemistry and are commencing in semester 2). You should also take the Chemistry Bridging Course in advance (offered in February, and online year-round https://sydney.edu.au/students/bridging-courses.html).
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions like how do dyes work, how do we desalinate water, how do we measure the acid content in foods, how do we get the blue in a blueprint, and how do we extract natural products from plants? Through inquiry, observation and measurement, you will understand the 'why' and the 'how' of the natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a satisfactory prior knowledge of the HSC chemistry course.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1911 Chemistry 1A (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1991 Assumed knowledge: 80 or above in HSC Chemistry or equivalent Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for broad application, including further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups of molecules. You will develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through inquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. This unit of study is directed toward students with a good secondary performance both overall and in chemistry or science. Students in this category are expected to do this unit rather than Chemistry 1A. Compared to the mainstream Chemistry 1A, the theory component of this unit provides a higher level of academic rigour and makes broader connections between topics.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1991 Chemistry 1A (Special Studies Program)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prohibitions: CHEM1001 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1109 or CHEM1011 or CHEM1111 or CHEM1911 Assumed knowledge: 90 or above in HSC Chemistry or equivalent Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Department permission required for enrolment
Chemistry describes how and why things happen from a molecular perspective. Chemistry underpins all aspects of the natural and physical world, and provides the basis for new technologies and advances in the life, medical and physical sciences, engineering, and industrial processes. This unit of study will further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, and further study in chemistry. You will learn about nuclear and radiation chemistry, wave theory, atomic orbitals, spectroscopy, bonding, enthalpy and entropy, equilibrium, processes occurring in solutions, and the functional groups in carbon chemistry. You will develop experimental design, conduct and analysis skills in chemistry in small group projects. The laboratory program is designed to extend students who already have chemistry laboratory experience, and particularly caters for students who already show a passion and enthusiasm for research chemistry, as well as aptitude as demonstrated by high school chemistry results. Entry to Chemistry 1A (Special Studies Program) is restricted to a small number of students with an excellent school record in Chemistry, and applications must be made to the School of Chemistry. The practical work syllabus for Chemistry 1A (Special Studies Program) is very different from that for Chemistry 1A and Chemistry 1A (Advanced) and consists of special project-based laboratory exercises. All other unit of study details are the same as those for Chemistry 1A (Advanced).
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1012 Fundamentals of Chemistry 1B

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: CHEM1XX1 Prohibitions: CHEM1002 or CHEM1102 or CHEM1902 or CHEM1904 or CHEM1108 or CHEM1112 or CHEM1912 or CHEM1992 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Chemistry transforms the way we live. It provides the basis for understanding biological, geological and atmospheric processes, how medicines work, the properties of materials and substances, how beer is brewed, and for obtaining forensic evidence. This unit of study builds upon your prior knowledge of chemistry to further develop your knowledge and skills in chemistry for broad application. You will learn about organic chemistry reactions, structural determination, nitrogen chemistry, industrial processes, kinetics, electrochemistry, thermochemistry, phase behaviour, solubility equilibrium and chemistry of metals. You will further develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through enquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. Fundamentals of Chemistry 1B is built on a satisfactory prior knowledge of Fundamentals of Chemistry 1A. Compared to the mainstream Chemistry 1B, the theory component of this unit begins with more fundamental concepts, and does not cover, or goes into less detail about some topics. Progression to intermediate chemistry from this unit requires completion of an online supplementary course.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1112 Chemistry 1B

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive February,Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: CHEM1111 or CHEM1911 or CHEM1991 or CHEM1101 or CHEM1901 or CHEM1903 or (75 or above in CHEM1011 or CHEM1001) Prohibitions: CHEM1002 or CHEM1102 or CHEM1902 or CHEM1904 or CHEM1108 or CHEM1012 or CHEM1912 or CHEM1992 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Chemistry transforms the way we live. It provides the basis for understanding biological, geological and atmospheric processes, how medicines work, the properties of materials and substances, how beer is brewed, and for obtaining forensic evidence. This unit of study builds upon your prior knowledge of chemistry to further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, industrial processing, and further study in chemistry. You will learn about organic chemistry reactions, structural determination, nitrogen chemistry, industrial processes, kinetics, electrochemistry, thermochemistry, phase behaviours, solubility equilibrium and chemistry of metals. You will further develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions like how do we develop lotions that don't burn us, how do we measure UV absorption by sunscreens, how can we measure and alter soil pH, how are sticky things made, and how do we determine the concentration of vitamin C in juice? Through enquiry, observation and measurement, you will understand the 'why' and the 'how' of the natural and physical world and will be able to apply this understanding to real-world problems and solutions. Chemistry 1B is built on a satisfactory prior knowledge of Chemistry 1A.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1912 Chemistry 1B (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: CHEM1911 or CHEM1991 or CHEM1901 or CHEM1903 or (75 or above in CHEM1111 or CHEM1101) or (90 or above in HSC Chemistry or equivalent) Prohibitions: CHEM1002 or CHEM1102 or CHEM1902 or CHEM1904 or CHEM1108 or CHEM1012 or CHEM1112 or CHEM1992 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Students who commence in semester 2 are strongly advised that you would be better served by taking the mainstream level units in sequence, Chemistry 1A before Chemistry 1B, rather than the Advanced units in the opposite order.
Chemistry transforms the way we live. It provides the basis for understanding biological, geological and atmospheric processes, how medicines work, the properties of materials and substances, how beer is brewed, and for obtaining forensic evidence. This unit of study builds upon your prior knowledge of chemistry to further develop your knowledge and skills in chemistry for broad application, including further study in chemistry. You will learn about organic chemistry reactions, structural determination, nitrogen chemistry, industrial processes, kinetics, electrochemistry, thermochemistry, phase behaviour, solubility equilibrium and chemistry of metals. You will further develop experimental design, conduct and analysis skills in chemistry through experiments that ask and answer questions about the chemical nature and processes occurring around you. Through enquiry, observation and measurement, you will better understand natural and physical world and will be able to apply this understanding to real-world problems and solutions. Chemistry 1B (Advanced) is built on a satisfactory prior knowledge of Chemistry 1A (Advanced). Compared to the mainstream Chemistry 1B, the theory component of this unit provides a higher level of academic rigour and makes broader connections between topics.
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)
CHEM1992 Chemistry 1B (Special Studies Program)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 75 or above in CHEM1991 or CHEM1903 or (90 or above in HSC Chemistry or equivalent) Prohibitions: CHEM1002 or CHEM1102 or CHEM1902 or CHEM1904 or CHEM1108 or CHEM1012 or CHEM1112 or CHEM1912 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Entry is by invitation. This unit of study is deemed to be an Advanced unit of study. Students who commence in semester 2 are strongly advised that you would be better served by taking the mainstream level units in sequence, Chemistry 1A before Chemistry 1B, rather than the Special Studies Program units in the opposite order.
Chemistry transforms the way we live. It provides the basis for understanding biological, geological and atmospheric processes, how food and medicines work, the properties of materials and substances. This unit of study builds upon your prior knowledge of chemistry to further develop your knowledge and skills in chemistry for application to life and medical sciences, engineering, industrial processing, and further study in chemistry. You will learn about organic chemistry reactions, structural determination, nitrogen chemistry, industrial processes, kinetics, electrochemistry, thermochemistry, phase behaviour, solubility equilibrium and chemistry of metals. You will develop experimental design, conduct and analysis skills in chemistry in small group projects. The laboratory program is designed to extend students, and particularly caters for students who already show a passion and enthusiasm for research chemistry, as well as a demonstrated aptitude. Chemistry 1B (Special Studies Program) is restricted to students who have gained a Distinction in Chemistry 1A (Special Studies Program) or by invitation. The practical work syllabus for Chemistry 1B (Special Studies Program) is very different from that for Chemistry 1B and Chemistry 1B (Advanced) and consists of special project-based laboratory exercises. All other unit of study details are the same as those for Chemistry 1B (Advanced).
Textbooks
Recommended textbook: Blackman, Bottle, Schmid, Mocerino and Wille,Chemistry, 3rd Edition, 2015 (John Wiley) ISBN: 978-0-7303-1105-8 (paperback) or 978-0-7303-2492-8 (e-text)

2000-level units of study

Core
CHEM2521 Molecular Stability and Reactivity

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: (CHEM1011 or CHEM1111 or CHEM1911 or CHEM1991 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1001) and (CHEM1012 or CHEM1112 or CHEM1912 or CHEM1992 or CHEM1102 or CHEM1902 or CHEM1904 or CHEM1002 ) Prohibitions: CHEM2921 or CHEM2991 or CHEM2401 or CHEM2911 or CHEM2915 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
There are over 144 million chemical substances so far identified, a diversity that makes possible the rich fabric of the material and biological worlds. Underpinning this huge diversity are a few fundamental rules of electronic arrangements in atoms and molecules that determine what molecules will be stable and when they will undergo transformation by chemical reaction. This unit will describe these fundamental rules and investigate how electronic rearrangements stabilise molecules by forming covalent bonds. You will investigate the quantum theory of bonding and apply these concepts to establish the rules that govern bond geometries, aromaticity, substitution and elimination reactions. You will investigate the bonding of metal complexes and the relation between magnetism and structure in these compounds. You will learn the fundamentals of electronic and vibrational spectroscopies and how these techniques are used to measure molecular properties. By doing this unit you will develop the fundamental understanding of chemical stability and reactivity essential for further work in all chemically related fields and have established a solid foundation for further study in chemistry.
CHEM2921 Molecular Stability and Reactivity (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 65 or above in (CHEM1111 or CHEM1911 or CHEM1991 or CHEM1011 or CHEM1101 or CHEM1901 or CHEM1903 or CHEM1001) and a mark of 65 or above in (CHEM1112 or CHEM1912 or CHEM1992 or CHEM1012 or CHEM1102 or CHEM1902 or CHEM1904 or CHEM1002) Prohibitions: CHEM2521 or CHEM2991 or CHEM2401 or CHEM2911 or CHEM2915 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
There are over 144 million chemical substances so far identified, a diversity that makes possible the rich fabric of the material and biological worlds. Underpinning this huge diversity are a few fundamental rules of electronic arrangements in atoms and molecules that determine what molecules will be stable and when they will undergo transformation by chemical reaction. This unit will describe these fundamental rules and investigate how electronic rearrangements stabilise molecules by forming covalent bonds. You will investigate the quantum theory of bonding and apply these concepts to establish the rules that govern bond geometries, aromaticity, substitution and elimination reactions. You will investigate the bonding of metal complexes and the relation between magnetism and structure in these compounds. You will learn the fundamentals of electronic and vibrational spectroscopies and how these techniques are used to measure molecular properties. Molecular Stability and Reactivity (Adv) differs from CHEM2521 in that the laboratory consists of open-ended discovery-oriented exercises. By doing this unit you will develop the fundamental understanding of chemical stability and reactivity essential for further work in all chemically related fields and have established a solid foundation for further study in chemistry.
CHEM2991 Molecular Stability and Reactivity (SSP)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 75 or above in (CHEM1111 or CHEM1911 or CHEM1991 or CHEM1011 or CHEM1901 or CHEM1903 or CHEM1011 or CHEM1001) and a mark of 75 or above in (CHEM1112 or CHEM1912 or CHEM1992 or CHEM1012 or CHEM1902 or CHEM1904 or CHEM1002) Prohibitions: CHEM2921 or CHEM2521 or CHEM2401 or CHEM2911 or CHEM2915 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
There are over 144 million chemical substances so far identified, a diversity that makes possible the rich fabric of the material and biological worlds. Underpinning this huge diversity are a few fundamental rules of electronic arrangements in atoms and molecules that determine what molecules will be stable and when they will undergo transformation by chemical reaction. This unit will describe these fundamental rules and investigate how electronic rearrangements stabilise molecules by forming covalent bonds. You will investigate the quantum theory of bonding and apply these concepts to establish the rules that govern bond geometries, aromaticity, substitution and elimination reactions. You will investigate the bonding of metal complexes and the relation between magnetism and structure in these compounds. You will learn the fundamentals of electronic and vibrational spectroscopies and how these techniques are used to measure molecular properties. Molecular Stability and Reactivity (SSP) differs from CHEM2921 in that it includes an additional seminar series on three research-led topics in chemistry. By doing this unit you will develop the fundamental understanding of chemical stability and reactivity essential for further work in all chemically related fields and have established a solid foundation for further study in chemistry.
PCOL coded
PCOL2021 Key Concepts in Pharmacology

Credit points: 6 Teacher/Coordinator: Dr Hilary Lloyd Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: CHEM1XX1 or CHEM1903 Prohibitions: PCOL2555 or PCOL2011 or MEDS2002 or BMED2401 or BMED2801 or BMED2802 or BMED2804 or BMED2805 or BMED2806 or BMED2807 or BMED2808 or MEDS2002 Assumed knowledge: [(BIOL1XX7 or MBLG1XX1) or (MEDS1X01 or BIOL1XX8 or BIOL1XX3) Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
Pharmacology is the study of the properties and biological actions of drugs and chemicals and the keys role they play in the prevention and treatment of human diseases. In this unit of study you will be introduced to the fundamental concepts in pharmacology: a) principles of drug action, b) pharmacokinetics and precision medicine, c) drug design, and d) drug development and regulation. Additionally, you will learn the tools pharmacologists use in their investigations and develop skills in laboratory and problem-based enquiry. In both face-to-face and online learning environments you will learn the core concepts underpinning pharmacology and will have the opportunity to explore and apply these concepts through practicals, computer-aided learning and problem-based workshops. By undertaking this unit you will not only learn to view health and disease through the lens of a pharmacologist, you will further develop valuable skills in critical thinking and problem solving, communication, digital literacy, teamwork and interdisciplinary effectiveness. This unit will help you to develop a coherent and connected knowledge of the medical sciences and their broad applications, while also giving you the foundations for increasing your disciplinary expertise in pharmacology.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
MEDS coded pharmacology
MEDS2002 Key Concepts in Pharmacology

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: CHEM1XX1 or CHEM1903 Prohibitions: PCOL2555 or PCOL2011 or PCOL2021 or BMED2401 or BMED2801 or BMED2802 or BMED2804 or BMED2805 or BMED2806 or BMED2807 or BMED2808 Assumed knowledge: [(BIOL1XX7 or MBLG1XX1) or (MEDS1X01 or BIOL1XX8 or BIOL1XX3) Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: This unit must be taken by all students enrolled in the BSc (Medical Science)
Pharmacology is the study of the properties and biological actions of drugs and chemicals and the keys role they play in the prevention and treatment of human diseases. In this unit of study you will be introduced to the fundamental concepts in pharmacology: a) principles of drug action, b) pharmacokinetics and precision medicine, c) drug design, and d) drug development and regulation. Additionally, you will learn the tools pharmacologists use in their investigations and develop skills in laboratory and problem-based enquiry. In both face-to-face and online learning environments you will learn the core concepts underpinning pharmacology and will have the opportunity to explore and apply these concepts through practicals, computer-aided learning and problem-based workshops. By undertaking this unit you will not only learn to view health and disease through the lens of a pharmacologist, you will further develop valuable skills in critical thinking and problem solving, communication, digital literacy, teamwork and interdisciplinary effectiveness. This unit will help you to develop a coherent and connected knowledge of the medical sciences and their broad applications, while also giving you the foundations for increasing your disciplinary expertise in pharmacology.
Textbooks
All resources will be made available through the Canvas LMS UoS site. Links to other learning technologies will be available via Canvas LMS. Textbooks will be available for purchase from Co-op bookshop, in hard copy and online via the library.
(MEDS coded unit of study are only available to students in the Medical Science stream).

3000-level units of study

Major Core
MCHM3001 From Molecules to Therapeutics

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: [(PCOL2011 or PCOL2021 or MEDS2002) or (BMED2401 and BMED2402) or (BMED2401 and BMED2405)] or (12cp from BCMB2XXX) and [(CHEM2401 or CHEM2521 or CHEM2911 or CHEM2915 or CHEM2921 or CHEM2991)] Prohibitions: MCHM3901 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Workshops and labs up to 4hr/week for 12 wks Mode of delivery: Normal (lecture/lab/tutorial) day
Major changes to the way we discover and develop new medicines have taken place in recent years. Sequencing of the human genome has revolutionised drug target identification and therapeutic design. Approaches that combine molecular biology and intensive data analysis are key to the development of effective personalised and precision therapies. New methods in organic synthesis have accelerated how we explore chemical space and parallel developments in nanotechnology are driving innovative drug delivery methods. Improvements in cell, tissue and animal models of human disease are changing how drugs are identified and tested. In this unit, you will explore how these new ideas and technologies are transforming medicinal chemistry. You will learn and apply such techniques to the molecular-level understanding of diseases and the design of effective therapeutics. You will learn the procedures leading to drug registration and regulation. You will participate in enquiry-led practicals that reinforce the concepts of the unit and develop your skills in cutting-edge methods used in modern medicinal chemistry. By studying this unit you will build knowledge and skills that will enable you to play a role in creating therapeutics that will impact lives.
MCHM3901 From Molecules to Therapeutics (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 70 or above in each of [(PCOL2011 or PCOL2021 or MEDS2002) or (BMED2401 and BMED2402) or (BMED2401 and BMED2405) or in each unit of (12cp from BCMB2XXX)] AND a mark of 70 or above in [(CHEM2401 or CHEM2521 or CHEM2911 or CHEM2915 or CHEM2921 or CHEM2991)] Prohibitions: MCHM3001 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: workshops and labs up to 4hr/week for 12 wks. Students in the Advanced unit of study will work in smaller groups and tackle alternative higher-level tasks in workshops and labs that broaden and extend their knowledge and expertise. Mode of delivery: Normal (lecture/lab/tutorial) day
Major changes to the way we discover and develop new medicines have taken place in recent years. Sequencing of the human genome has revolutionised drug target identification and therapeutic design. Genomics approaches that combine molecular biology and intensive data analysis are key to the development of personalised and precision therapies. New methods in organic synthesis have accelerated how we explore chemical space, developments in nanotechnology are driving innovative drug delivery methods. In this unit you will explore how these new ideas and technologies transforming medicinal chemistry. You will learn and apply such techniques to the molecular-level understanding of diseases and the design of effective therapeutics. You will learn the procedures leading to drug registration and regulation. You will participate in enquiry-led practicals that reinforce the concepts of the unit and develop your skills in cutting-edge methods used in modern medicinal chemistry. By studying this unit you will build knowledge and skills that will enable you to play a role in creating therapeutics that will impact lives. You will learn and apply such techniques to the molecular-level understanding of diseases and the design of effective therapeutics. The advanced unit has the same overall concepts as the mainstream unit but the material is discussed in a manner that offers a greater level of challenge and academic rigour. Students enrolled in the advanced stream will participate in alternative components, which may vary from year to year.
PCOL3012 Drug Design and Development

Credit points: 6 Teacher/Coordinator: Dr Brent McParland Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: (PCOL2011 or PCOL2021 or MEDS2002) or [BMED2401 and 6cp from (BMED2402 or BMED2405)] or 12cp from BCMB2XXX Prohibitions: PCOL3912 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This unit of study is designed to introduce students with a basic understanding of pharmacology to the field of medicinal chemistry associated with drug design and development. The course covers the fundamental aspects of drug discovery and development with reference to the essentials of chemistry and illustrates drug development with examples that include neuraminidase inhibitors and angiotensin converting enzyme inhibitors. The role of computers in drug design is emphasised by classwork and assignments on molecular modelling and structure-activity relationships. The course also extends to a section on the design of diverse pharmacological agents which include compounds for imaging by positron emission tomography (PET), and kinase inhibitors.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
PCOL3912 Drug Design and Development (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Brent McParland Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: a mark of 70 or above in {(PCOL2011 or PCOL2021 or MEDS2002) or [BMED2401 and 6cp from (BMED2402 or BMED2405)] or 12cp from BCMB2XXX} Prohibitions: PCOL3012 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This unit will consist of the lecture and practical components of PCOL3012. Students will be set special advanced assignments related to the material covered in core areas. These may also involve advanced practical work or detailed investigation of a theoretical problem.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
Chemistry selective
CHEM3118 Synthetic Chemistry

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3115 or CHEM3915 or CHEM3918 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Over 144 million chemical substances are known, many of which possess a complex arrangement of atoms and bonds that lead to unique and intricate 3-dimensional structures. Chemical structure is directly related to the function of molecules. While the structures of many known compounds have been built using the limited set of reactions that are employed by Nature, not all chemical structures can be accessed this way. Synthetic chemists have developed a multitude of reactions and strategies to build molecules that can't be accessed using Nature's toolkit. These can be applied to the creation of manufactured chemicals that improve our everyday lives, including medicines, fabrics, coatings, and in food production.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CHEM3918 Synthetic Chemistry (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 65 or greater in [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or a mark of 65 or greater in (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3115 or CHEM3915 or CHEM3118 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Over 144 million chemical substances are known, many of which possess a complex arrangement of atoms and bonds that lead to unique and intricate 3-dimensional structures. Chemical structure is directly related to the function of molecules. While the structures of many known compounds have been built using the limited set of reactions that are employed by Nature, not all chemical structures can be accessed this way. Synthetic chemists have developed a multitude of reactions and strategies to build molecules that can't be accessed using Nature's toolkit. These can be applied to the creation of manufactured chemicals that improve our everyday lives, including medicines, fabrics, coatings, and in food production. In this unit you will learn fundamental strategies and reactions that can be used to create new molecular structures. You will investigate strategies that allow the synthesis of specific isomers to interact with the chiral world we live in, including molecules that cure disease. You will learn modern synthetic reaction methods that mitigate the environmental impact of chemical synthesis. By doing this unit you will develop an understanding of how chemical bonds can be broken and formed in a directed manner to build new molecular architectures with specific properties and 3-dimensional shapes.Advanced students attend an additional advanced seminar series to gain more in-depth disciplinary knowledge where they actively engage with a diverse range of contemporary chemical research problems and case studies. They gain additional opportunities to develop skills in collaborative work and enhance their written and oral communication skills.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CHEM3121 Chemical Biology

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3110 or CHEM3910 or CHEM3921 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
The importance of chemistry to understand the inner workings of biology has led to the emergence of the field of chemical biology. In recent years, the development of cutting-edge synthetic methods, as well as analytical and imaging technologies, have underpinned advances in drug discovery, diagnostics, genome sequencing and biocatalysis. In this unit, you will learn how chemical structure and reactivity underpins the function of all nature's biomolecules, from the enzymes that enable chemical reactions to occur inside cells, to the DNA featuring chemical modifications that affect how the genetic code is read. You will also learn how the development and application of modern synthetic chemistry can be used to generate designer biomolecules to perturb, manipulate and visualise cellular processes. Key examples include how we can synthesise an entire protein using synthetic chemistry alone, and how we can use fluorescent dyes to observe what is happening in live cells as a result of disease. You will gain insight into the rapidly advancing field of chemical biology, and how new chemistry-based technologies are being used to solve major problems in biology and medicine.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CHEM3921 Chemical Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 65 or greater in [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or a mark of 65 or greater in (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3110 or CHEM3121 or CHEM3910 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
The importance of chemistry to understand the inner workings of biology has led to the emergence of the field of chemical biology. In recent years, the development of cutting-edge synthetic methods, as well as analytical and imaging technologies, have underpinned advances in drug discovery, diagnostics, genome sequencing and biocatalysis. In this unit, you will learn how the structure and reactivity of nature's biomolecules underpins their function. You will also learn how the development and application of modern synthetic chemistry can be used to generate designer biomolecules to perturb, manipulate and visualise cellular processes. By completing this unit, you will gain insight into the rapidly advancing field of chemical biology, and how new chemistry-based technologies are being used to solve major problems in biology and medicine. Advanced students attend in addition an advanced seminar series to gain more in-depth disciplinary knowledge where they actively engage with a diverse range of contemporary chemical research problems and case studies. They gain additional opportunities to develop skills in collaborative work and enhance their written and oral communication skills.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
Interdisciplinary Project
MCHM3888 Medicinal Chemistry Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: (CHEM2401 or CHEM2521 or CHEM2911 or CHEM2915 or CHEM2921 or CHEM2991) and [(PCOL2011 or PCOL2021 or MEDS2002) or (BMED2401 and {BMED2402 or BMED2405})] Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
In this unit, you will adopt a multi-disciplinary approach to solve a real-world problem based around treating a disease relevant to our society, such as cancer, heart disease, infection or neurological conditions. You will apply your discipline expertise in medicinal chemistry to understand the challenge, then design potential solutions to the problem, and then work collaboratively with students in other disciplines (science, government, business, law, marketing, engineering) to consider solutions to the problem from a broader perspective and how these could positively impact on the community. This unit will allow you to understand the disease through stories of scientific endeavour that led to the discovery of first-generation drugs, then extend that knowledge through collecting and analysing data on new treatment solutions that can help you move towards designing innovative approaches. You will learn to work in interdisciplinary teams and communicate your findings to a broad audience. You will build key skills in problem solving, team work and written/oral communication that will equip you for many future research or professional pathways in one or more of: science, technology, health, business and public policy.
SCPU3001 Science Interdisciplinary Project

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive February,Intensive July,Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 96 credit points Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
This interdisciplinary unit provides students with the opportunity to address complex problems identified by industry, community, and government organisations, and gain valuable experience in working across disciplinary boundaries. In collaboration with a major industry partner and an academic lead, students integrate their academic skills and knowledge by working in teams with students from a range of disciplinary backgrounds. This experience allows students to research, analyse and present solutions to a real¿world problem, and to build on their interpersonal and transferable skills by engaging with and learning from industry experts and presenting their ideas and solutions to the industry partner.
Minor Core
MCHM3001 From Molecules to Therapeutics

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: [(PCOL2011 or PCOL2021 or MEDS2002) or (BMED2401 and BMED2402) or (BMED2401 and BMED2405)] or (12cp from BCMB2XXX) and [(CHEM2401 or CHEM2521 or CHEM2911 or CHEM2915 or CHEM2921 or CHEM2991)] Prohibitions: MCHM3901 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Workshops and labs up to 4hr/week for 12 wks Mode of delivery: Normal (lecture/lab/tutorial) day
Major changes to the way we discover and develop new medicines have taken place in recent years. Sequencing of the human genome has revolutionised drug target identification and therapeutic design. Approaches that combine molecular biology and intensive data analysis are key to the development of effective personalised and precision therapies. New methods in organic synthesis have accelerated how we explore chemical space and parallel developments in nanotechnology are driving innovative drug delivery methods. Improvements in cell, tissue and animal models of human disease are changing how drugs are identified and tested. In this unit, you will explore how these new ideas and technologies are transforming medicinal chemistry. You will learn and apply such techniques to the molecular-level understanding of diseases and the design of effective therapeutics. You will learn the procedures leading to drug registration and regulation. You will participate in enquiry-led practicals that reinforce the concepts of the unit and develop your skills in cutting-edge methods used in modern medicinal chemistry. By studying this unit you will build knowledge and skills that will enable you to play a role in creating therapeutics that will impact lives.
MCHM3901 From Molecules to Therapeutics (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 70 or above in each of [(PCOL2011 or PCOL2021 or MEDS2002) or (BMED2401 and BMED2402) or (BMED2401 and BMED2405) or in each unit of (12cp from BCMB2XXX)] AND a mark of 70 or above in [(CHEM2401 or CHEM2521 or CHEM2911 or CHEM2915 or CHEM2921 or CHEM2991)] Prohibitions: MCHM3001 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: workshops and labs up to 4hr/week for 12 wks. Students in the Advanced unit of study will work in smaller groups and tackle alternative higher-level tasks in workshops and labs that broaden and extend their knowledge and expertise. Mode of delivery: Normal (lecture/lab/tutorial) day
Major changes to the way we discover and develop new medicines have taken place in recent years. Sequencing of the human genome has revolutionised drug target identification and therapeutic design. Genomics approaches that combine molecular biology and intensive data analysis are key to the development of personalised and precision therapies. New methods in organic synthesis have accelerated how we explore chemical space, developments in nanotechnology are driving innovative drug delivery methods. In this unit you will explore how these new ideas and technologies transforming medicinal chemistry. You will learn and apply such techniques to the molecular-level understanding of diseases and the design of effective therapeutics. You will learn the procedures leading to drug registration and regulation. You will participate in enquiry-led practicals that reinforce the concepts of the unit and develop your skills in cutting-edge methods used in modern medicinal chemistry. By studying this unit you will build knowledge and skills that will enable you to play a role in creating therapeutics that will impact lives. You will learn and apply such techniques to the molecular-level understanding of diseases and the design of effective therapeutics. The advanced unit has the same overall concepts as the mainstream unit but the material is discussed in a manner that offers a greater level of challenge and academic rigour. Students enrolled in the advanced stream will participate in alternative components, which may vary from year to year.
Minor selective
CHEM3118 Synthetic Chemistry

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3115 or CHEM3915 or CHEM3918 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Over 144 million chemical substances are known, many of which possess a complex arrangement of atoms and bonds that lead to unique and intricate 3-dimensional structures. Chemical structure is directly related to the function of molecules. While the structures of many known compounds have been built using the limited set of reactions that are employed by Nature, not all chemical structures can be accessed this way. Synthetic chemists have developed a multitude of reactions and strategies to build molecules that can't be accessed using Nature's toolkit. These can be applied to the creation of manufactured chemicals that improve our everyday lives, including medicines, fabrics, coatings, and in food production.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CHEM3918 Synthetic Chemistry (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 65 or greater in [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or a mark of 65 or greater in (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3115 or CHEM3915 or CHEM3118 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Over 144 million chemical substances are known, many of which possess a complex arrangement of atoms and bonds that lead to unique and intricate 3-dimensional structures. Chemical structure is directly related to the function of molecules. While the structures of many known compounds have been built using the limited set of reactions that are employed by Nature, not all chemical structures can be accessed this way. Synthetic chemists have developed a multitude of reactions and strategies to build molecules that can't be accessed using Nature's toolkit. These can be applied to the creation of manufactured chemicals that improve our everyday lives, including medicines, fabrics, coatings, and in food production. In this unit you will learn fundamental strategies and reactions that can be used to create new molecular structures. You will investigate strategies that allow the synthesis of specific isomers to interact with the chiral world we live in, including molecules that cure disease. You will learn modern synthetic reaction methods that mitigate the environmental impact of chemical synthesis. By doing this unit you will develop an understanding of how chemical bonds can be broken and formed in a directed manner to build new molecular architectures with specific properties and 3-dimensional shapes.Advanced students attend an additional advanced seminar series to gain more in-depth disciplinary knowledge where they actively engage with a diverse range of contemporary chemical research problems and case studies. They gain additional opportunities to develop skills in collaborative work and enhance their written and oral communication skills.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CHEM3121 Chemical Biology

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3110 or CHEM3910 or CHEM3921 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
The importance of chemistry to understand the inner workings of biology has led to the emergence of the field of chemical biology. In recent years, the development of cutting-edge synthetic methods, as well as analytical and imaging technologies, have underpinned advances in drug discovery, diagnostics, genome sequencing and biocatalysis. In this unit, you will learn how chemical structure and reactivity underpins the function of all nature's biomolecules, from the enzymes that enable chemical reactions to occur inside cells, to the DNA featuring chemical modifications that affect how the genetic code is read. You will also learn how the development and application of modern synthetic chemistry can be used to generate designer biomolecules to perturb, manipulate and visualise cellular processes. Key examples include how we can synthesise an entire protein using synthetic chemistry alone, and how we can use fluorescent dyes to observe what is happening in live cells as a result of disease. You will gain insight into the rapidly advancing field of chemical biology, and how new chemistry-based technologies are being used to solve major problems in biology and medicine.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
CHEM3921 Chemical Biology (Advanced)

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: A mark of 65 or greater in [(CHEM2401 or CHEM2911 or CHEM2915) and (CHEM2402 or CHEM2524 or CHEM2912 or CHEM2916 or CHEM2924)] or a mark of 65 or greater in (CHEM2521 or CHEM2921 or CHEM2991) Prohibitions: CHEM3110 or CHEM3121 or CHEM3910 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
The importance of chemistry to understand the inner workings of biology has led to the emergence of the field of chemical biology. In recent years, the development of cutting-edge synthetic methods, as well as analytical and imaging technologies, have underpinned advances in drug discovery, diagnostics, genome sequencing and biocatalysis. In this unit, you will learn how the structure and reactivity of nature's biomolecules underpins their function. You will also learn how the development and application of modern synthetic chemistry can be used to generate designer biomolecules to perturb, manipulate and visualise cellular processes. By completing this unit, you will gain insight into the rapidly advancing field of chemical biology, and how new chemistry-based technologies are being used to solve major problems in biology and medicine. Advanced students attend in addition an advanced seminar series to gain more in-depth disciplinary knowledge where they actively engage with a diverse range of contemporary chemical research problems and case studies. They gain additional opportunities to develop skills in collaborative work and enhance their written and oral communication skills.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
PCOL3012 Drug Design and Development

Credit points: 6 Teacher/Coordinator: Dr Brent McParland Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: (PCOL2011 or PCOL2021 or MEDS2002) or [BMED2401 and 6cp from (BMED2402 or BMED2405)] or 12cp from BCMB2XXX Prohibitions: PCOL3912 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This unit of study is designed to introduce students with a basic understanding of pharmacology to the field of medicinal chemistry associated with drug design and development. The course covers the fundamental aspects of drug discovery and development with reference to the essentials of chemistry and illustrates drug development with examples that include neuraminidase inhibitors and angiotensin converting enzyme inhibitors. The role of computers in drug design is emphasised by classwork and assignments on molecular modelling and structure-activity relationships. The course also extends to a section on the design of diverse pharmacological agents which include compounds for imaging by positron emission tomography (PET), and kinase inhibitors.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
PCOL3912 Drug Design and Development (Advanced)

Credit points: 6 Teacher/Coordinator: Dr Brent McParland Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: a mark of 70 or above in {(PCOL2011 or PCOL2021 or MEDS2002) or [BMED2401 and 6cp from (BMED2402 or BMED2405)] or 12cp from BCMB2XXX} Prohibitions: PCOL3012 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
This unit will consist of the lecture and practical components of PCOL3012. Students will be set special advanced assignments related to the material covered in core areas. These may also involve advanced practical work or detailed investigation of a theoretical problem.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units