Medicinal Chemistry

Unit outlines will be available through Find a unit outline two weeks before the first day of teaching for 1000-level and 5000-level units, or one week before the first day of teaching for all other units.
 

MEDICINAL CHEMISTRY (HONOURS)

The Bachelor of Advanced Studies (Honours) (Medicinal Chemistry) requires 48 credit points from this table including:
(i) 6 credit points of 4000-level Honours selective units from List 1, and
(ii) 6 credit points of 4000-level Honours selective units from List 2, and
(iii) 36 credit points of 4000-level Honours research project units

Honours Coursework Selective

List 1
CHEM4101 Chemistry Research Skills

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: (CHEM3X11 and CHEM3X15) or (24 cp of CHEM3XXX or (18 cp of CHEM3XXX and SCPU3001)) Assumed knowledge: Proficiency in safe chemical laboratory practices. Completion of a senior level laboratory course. Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Chemical research involves the identification of a problem worthy of investigation, formulation of a hypothesis, the design of experiments and the communication of the outcomes of the research. This unit focuses on the preparation of a research proposal that should be distinct from your Honours project work currently being undertaken in the School of Chemistry. You will, in consultation with a member of the academic staff and the unit coordinator, develop a research proposal that provides an account of the relevant scientific literature that leads to the identification of specific research aims. The proposal will describe the methodologies needed to test your hypothesis and demonstrate the feasibility of these by reference to the existing literature and the significance of the research. You will present a short seminar based on you proposal. This unit will also introduce you to the relevant workplace health and safety requirements. By completing this unit you will be prepared to develop and initiate a chemical research project.
SOMS4101 Research Skills for Medical Sciences

Credit points: 6 Teacher/Coordinator: Najla Nasr and Paul Austin Session: Intensive August,Intensive March Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Assumed knowledge: A major in one of the following areas: Applied Medical Science; Immunology and Pathology; Biochemistry and Molecular Biology; Biology; Microbiology; Cell and Developmental Biology; Infectious Diseases; Pharmacology; Medicinal Chemistry; Neuroscience; Physiology; Anatomy and Histology; Genetics and Genomics; Quantitaive Life Science Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Block mode
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
We face major health challenges in today's society that require new insights and approaches from bright minds. Tackling the big questions in medical sciences and health requires the research skills that will inform tomorrow's health outcomes for individuals and populations. Immersed in a multidisciplinary medical science and health research environment, you will develop the core skills required to undertake laboratory, clinical and population health research. You will learn to design, execute and evaluate studies, and to scrutinise data and research outcomes. You will work individually and collaboratively in small teams of students from different areas of specialisation to learn theoretical and practical aspects of specific research techniques, as well as the ethical and regulatory frameworks relevant to medical and health research. This unit of study will equip you with knowledge and skills that will enable you to play an active role in finding meaningful solutions to difficult problems in a technical or research setting.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units
List 2
SCIE4001 Science Communication

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 144 credit points of units of study and including a minimum of 24 credit points at the 3000- or 4000-level and 18 credit points of 3000- or 4000-level units from Science Table A. Assumed knowledge: Completion of a major in a science discipline. Basic knowledge of other sciences is beneficial. Experience in communication such as delivering oral presentations and producing written reports. An awareness of science in a societal context, e.g., of disciplinary applications. Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Remote Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Mid-year honours students would take this unit of study in S1 (their second semester of study).
"If you can't explain it simply, you don't understand it well enough". This quote is widely attributed to Albert Einstein, but regardless of its provenance, it suggests that one measure of an expert's knowledge can be found in their ability to translate complex ideas so that they are accessible to anyone. The communication of science to the public is essential for science and society. In order to increase public understanding and appreciation of science, researchers must be able to explain their results, and the wider context of their research, to non-experts. This unit will explore some theoretical foundations of science communications, identify outstanding practitioners and empower students to produce effective science communication in different media. In this unit you will learn the necessary skills and techniques to tell engaging and informative science stories in order to bring complex ideas to life, for non-expert audiences. By undertaking this unit you will develop a greater understanding of the wider context of your honours unit, advance your communication skills and be able to explain your honours research to non-expert audiences such as friends, family or future employers. These transferable skills will equip you for future research - where emphasis is increasingly placed on public communication and/or outreach - or professional pathways - where effective communication of complex ideas is highly valued.
SCIE4002 Experimental Design and Data Analysis

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive March Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 144 credit points of units of study and including a minimum of 24 credit points at the 3000- or 4000-level and 18 credit points of 3000- or 4000-level units from Science Table A. Prohibitions: ENVX3002 or STAT3X22 or STAT4022 or STAT3X12 Assumed knowledge: Completion of units in quantitative research methods, mathematics or statistical analysis at least at 1000-level. Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Remote Mode of delivery: Block mode
An indispensable attribute of an effective scientific researcher is the ability to collect, analyse and interpret data. Central to this process is the ability to create hypotheses and test these by using rigorous experimental designs. This modular unit of study will introduce the key concepts of experimental design and data analysis. Specifically, you will learn to formulate experimental aims to test a specific hypothesis. You will develop the skills and understanding required to design a rigorous scientific experiment, including an understanding of concepts such as controls, replicates, sample size, dependent and independent variables and good research practice (e. g. blinding, randomisation). By completing this unit you will develop the knowledge and skills required to appropriately analyse and interpret data in order to draw conclusions in the context of an advanced research project. From this unit of study, you will emerge with a comprehensive understanding of how to optimise the design and analysis of an experiment to most effectively answer scientific questions.
SCIE4003 Ethics in Science

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Intensive August,Intensive March Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: 144 credit points of units of study and including a minimum of 24 credit points at the 3000- or 4000-level and 18 credit points of 3000- or 4000-level units from Science Table A Prohibitions: HSBH3004 or HPSC3107 Assumed knowledge: Successful completion of a Science major. Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Remote Mode of delivery: Block mode
In the contemporary world, a wide variety of ethical concerns impinge upon the practice of scientific research. In this unit you will learn how to identify potential ethical issues within science, acquire the tools necessary to analyse them, and develop the ability to articulate ethically sound insights about how to resolve them. In the first portion of the unit, you will be familiarised with how significant developments in post-World War II science motivated sustained ethical debate among scientists and in society. In the second portion of the unit, you will select from either a Human Ethics module or an Animal Ethics module and learn the requirements of how to ensure your research complies with appropriate national legislation and codes of conduct. By undertaking this unit you will develop the ability to conduct scientific research in an ethically justifiable way, place scientific developments and their application in a broader social context, and analyse the social implications and ethical issues that may potentially arise in the course of developing scientific knowledge.
SOMS4102 Communicating Ideas in Biomedical Science

Credit points: 6 Teacher/Coordinator: Andrew Harman and Lenka Munoz Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Prerequisites: SOMS4101 Assumed knowledge: A major in one of the following areas: Applied Medical Science; Immunology and Pathology; Biochemistry and Molecular Biology; Biology; Microbiology; Cell and Developmental Biology; Infectious Diseases; Pharmacology; Medicinal Chemistry; Neuroscience; Physiology; Anatomy and Histology; Genetics and Genomics; Quantitaive Life Science Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Practical field work: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
Note: Refer to the unit of study outline https://www.sydney.edu.au/units
The capacity to interpret a biological concept and communicate scientific findings is a fundamental skill underlying all facets of medical and health sciences. In this unit of study, you will develop the skills to critique a wide range of scientific literature from peer-reviewed articles to unsubstantiated independent web-site claims. You will learn how to critically assess the validity of scientific information to distinguish between rigorous, scientifically-supported claims and pseudoscience. You will also examine key concepts in data interpretation and evaluation in relation to medicine and health. This unit includes tasks that will enable you to clearly and independently communicate your own research findings both written and verbally to a range of audiences including politicians, the media, the general public and the wider scientific community. The skills taught in this unit will provide you with a solid foundation upon which you can forge a professional career in the health and medical communication sphere.
Textbooks
Refer to the unit of study outline https://www.sydney.edu.au/units

Honours Core Research Project

MCHM4103 Medicinal Chemistry Honours Project A

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will extend your undergraduate training in medicinal chemistry by undertaking a research project in an area of medicinal chemistry that interests you under the guidance and mentorship of a supervisor. Together with your supervisor, you will identify a novel research question and develop hypotheses. You will then design and carry out experiments to test your hypotheses. You will communicate the research plan and findings through written tasks and oral presentations culminating in an Honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for undertaking a PhD or for a variety of future careers.
MCHM4104 Medicinal Chemistry Honours Project B

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: MCHM4103 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will extend your undergraduate training in medicinal chemistry by undertaking a research project in an area of medicinal chemistry that interests you under the guidance and mentorship of a supervisor. Together with your supervisor, you will identify a novel research question and develop hypotheses. You will then design and carry out experiments to test your hypotheses. You will communicate the research plan and findings through written tasks and oral presentations culminating in an Honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for undertaking a PhD or for a variety of future careers.
MCHM4105 Medicinal Chemistry Honours Project C

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: MCHM4104 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will extend your undergraduate training in medicinal chemistry by undertaking a research project in an area of medicinal chemistry that interests you under the guidance and mentorship of a supervisor. Together with your supervisor, you will identify a novel research question and develop hypotheses. You will then design and carry out experiments to test your hypotheses. You will communicate the research plan and findings through written tasks and oral presentations culminating in an Honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for undertaking a PhD or for a variety of future careers.
MCHM4106 Medicinal Chemistry Honours Project D

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: MCHM4105 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will extend your undergraduate training in medicinal chemistry by undertaking a research project in an area of medicinal chemistry that interests you under the guidance and mentorship of a supervisor. Together with your supervisor, you will identify a novel research question and develop hypotheses. You will then design and carry out experiments to test your hypotheses. You will communicate the research plan and findings through written tasks and oral presentations culminating in an Honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for undertaking a PhD or for a variety of future careers.
MCHM4107 Medicinal Chemistry Honours Project E

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: MCHM4106 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will extend your undergraduate training in medicinal chemistry by undertaking a research project in an area of medicinal chemistry that interests you under the guidance and mentorship of a supervisor. Together with your supervisor, you will identify a novel research question and develop hypotheses. You will then design and carry out experiments to test your hypotheses. You will communicate the research plan and findings through written tasks and oral presentations culminating in an Honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for undertaking a PhD or for a variety of future careers.
MCHM4108 Medicinal Chemistry Honours Project F

Credit points: 6 Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Corequisites: MCHM4107 and SCIE4999 Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Supervision
Independent research can be a life changing experience. In this unit you will extend your undergraduate training in medicinal chemistry by undertaking a research project in an area of medicinal chemistry that interests you under the guidance and mentorship of a supervisor. Together with your supervisor, you will identify a novel research question and develop hypotheses. You will then design and carry out experiments to test your hypotheses. You will communicate the research plan and findings through written tasks and oral presentations culminating in an Honours thesis. Successful completion of your Honours will clearly demonstrate that you have mastered significant research and professional skills for undertaking a PhD or for a variety of future careers.
SCIE4999 Final Honours Mark

Teacher/Coordinator: Refer to the unit of study outline https://www.sydney.edu.au/units Session: Semester 1,Semester 2 Classes: Refer to the unit of study outline https://www.sydney.edu.au/units Assessment: Refer to the unit of study outline https://www.sydney.edu.au/units Campus: Camperdown/Darlington, Sydney Mode of delivery: Normal (lecture/lab/tutorial) day
All students in Science Honours must enrol in this non-assessable unit of study in their final semester. This unit will contain your final Honours mark as calculated from your coursework and research project units.