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The latest news from the Marie Bashir Institute

Articles

14 December 2020

Synthesis and Evaluation of a Series of Bis(pentylpyridinium) Compounds as Antifungal Agents

A series of bis(4‐pentylpyridinium) compounds with a variety of spacers between the pyridinium headgroups was synthesised, and the antifungal activity of these compounds was investigated. Lengthening the alkyl spacer between the pentylpyridinium headgroups from 12 to 16 methylene units resulted in increased antifungal activity against C. neoformans and C. albicans, but also resulted in increased hemolytic activity and cytotoxicity against mammalian cells.
14 December 2020

WHO priority pathogen list for fungi

Led by MBI's Fungisphere Node Leader, Dr Justin Beardsley, the team will develop a WHO priority pathogen list for fungi.
23 November 2020

Changes in public preferences for technologically enhanced surveillance following the COVID-19 pandemic: a discrete choice experiment

As governments attempt to navigate a path out of COVID-19 restrictions, robust evidence is essential to inform requirements for public acceptance of technologically enhanced communicable disease surveillance systems. We examined the value of core surveillance system attributes to the Australian public, before and during the early stages of the current pandemic.
16 November 2020

Modelling transmission and control of the COVID-19 pandemic in Australia

There is a continuing debate on relative benefits of various mitigation and suppression strategies aimed to control the spread of COVID-19. Here we report the results of agent-based modelling using a fine-grained computational simulation of the ongoing COVID-19 pandemic in Australia. This model is calibrated to match key characteristics of COVID-19 transmission.