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Combined, Correlative and Integrated Microscopy: Unraveling Biomolecular Structure-Function Activities in Cancer & Transendothelial Transport


Our team seek to understand the spatial and temporal mechanisms involved in the onset and progress of colorectal cancer by using state-of-the-art multidimensional microscopy and 3-D correlative imaging techniques. In this way, novel ultrastsructural information over micrometre-to-nanometre scales can be gathered to underpin the development and application of new targeted drug delivery strategies of for colorectal cancer.Other related work focuses on the development of 4-D simulation models of the colorectal tumour's in-vivo microenvironment in relevant organoid and animal models. In this work we explore the structure-function relationship of different subcellular compartments and molecules in various vascular models. 


Associate Professor Filip Braet.

Research location

Australian Centre for Microscopy & Microanalysis (ACMM)

Program type



This work will build on A/Prof. Braet's seminal work that cover the areas of structural biology, cancer biology, cell membrane biology, nanobiology, and chemical biology. 

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Opportunity ID

The opportunity ID for this research opportunity is 1502