My laboratory investigates the neuromuscular mechanisms underlying the transition from acute to chronic pain following musculoskeletal trauma (generally) and head/neck trauma (specifically) from a motor vehicle crash (MVC).
Many of our ongoing experiments focus on the use of structural and advanced magnetic resonance imaging (MRI) applications to quantify the temporal development of muscle degeneration and altered spinal cord anatomy as potential cellular and molecular substrates of persistent pain following whiplash injuries. Broad applications of our work includes preventing, diagnosing, and treating whiplash related pain and its sequelae. This research is based on clinical and research experience and has expanded through interdisciplinary efforts involving the fields of magnetic resonance physics, radiology, biomedical engineering, speech pathology, neurophysiology and physiotherapy.
Other ongoing and developing experimental lines include the quantification of biologically based stress/immune processes that are driven by stress-induced changes in microRNA (miRNA) expression that may play a role in the recovery process following traumatic injury.
Our research is focused on understanding the pathophysiological mechanisms underlying the transition from acute to chronic pain following traumatic injuries (generally) and whiplash injury from a motor vehicle collision (specifically). We use structural and advanced magnetic resonance imaging applications to quantify the temporal development of altered spinal cord physiology and muscle degeneration as potential cellular and molecular substrates of persistent pain-related disability.
The opportunity ID for this research opportunity is 2344