We have an exciting PhD project that is focused on understanding the interaction of cold atmospheric plasmas with microbial biofilms. Plasma is the fourth state of matter and forms when gas is exposed to an electrical charge producing a lightning-like discharge. A plasma discharge can also be made in water to generate plasma-activated water. Plasma and plasma-activated water have antimicrobial activity due to a range of reactive chemical species formed. A detailed understanding of its mode of action is required so that plasma technology can easily be applied to remove unwanted biofilms from food and food production equipment, water systems and medical devices.
The project aims to understand plasma interactions with biofilm cells and their extracellular matrix. The objective is to investigate structural and biomolecular changes of single and mixed-species biofilms using flow cell culturing, fluorescent microscopy, genomics and transcriptomics.
The position is based in Building F22, SOLES, Faculty of Science at the University of Sydney, Darlington/Camperdown campus but enrolment would be in Engineering.
The opportunity ID for this research opportunity is 2917