Research Supervisor Connect
This project aims to develop a versatile bioimaging workflow for multidimensional imaging of cell structures across different length scales, leveraging multiple imaging modalities to gather comprehensive data. By integrating micro-CT platforms with correlated light and electron microscopy (CLEM), the workflow seeks to enhance data collection and analysis, particularly focusing on regions of interest in a variety of biological samples.
Associate Professor Filip Braet.
Camperdown - School of Medical Sciences
This project aims to establish a highly versatile bioimaging workflow for multidimensional imaging of cell structures across vastly different length scales. Successful implementation of this novel approach will harness the fundamental advantages inherent to the various imaging modalities investigated. The combined modalities offers information not currently available by any single microscopy platform. Previously, we successfully implemented state-of-the-art approaches to correlate light and electron microscopy (CLEM) data. However, despite their effectiveness, the immense information within datasets hampered the collection of large quantities of data to permit rigorous statistical analysis. Herein, we will take advantage of our latest micro-CT platforms to record regions of interest (ROIs) in existing zebrafish samples in their relevant microanatomical context for subsequent CLEM analysis.
Research location: Sydney Microscopy & Microanalysis (Madsen Building F09)
The opportunity ID for this research opportunity is 3470