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Define regulatory control pathways delivering NPF (nitrate) and AMT (ammonium) transport activities across root types and cell profiles

We have previously identified the tissue expression patterns of ZmNPF6;6 and ZmNPF6;4 in maize root tips (Wen, Z., et al., The Plant Cell, 2017) and used qPCR as well as custom arra more...

Supervisor(s): Kaiser, Brent (Professor)

E-Coach-supported Digital SlEEp Therapy for Older ADults with Cognitive Impairment – the ExCEED Study

We are seeking a Master/PhD student to conduct a three-part study: (a) user experience qualitative study of older people's perceptions of Sleepfix; (b) randomised control trial of t more...

Supervisor(s): Gordon, Christopher (Dr), Hoyos, Camilla (Dr)

QUANTIFYING INTER-INDIVIDUAL VARIABILITY IN CIRCADIAN RHYTHMS

The overarching goal of this set of projects is to understand the brain mechanisms of inter-individual variability in circadian rhythms and develop tools for personalized prediction more...

Supervisor(s): Postnova, Svetlana (Dr)

MODELLING EFFECTS OF LIGHT ON THE CIRCADIAN RHYTHMS

This project aims to advance our understanding of the effects of light on the circadian rhythms and develop a detailed biophysical model of the circadian photoreceptor system that i more...

Supervisor(s): Postnova, Svetlana (Dr)

Defining the genetic link between nitrate and ammonium transport proteins and root architecture in Maize and Barley

We have previously tested two contrasting maize inbred lines on their inherent nitrate transport rates and respective responses to growth at low nitrogen supply. The lines were sele more...

Supervisor(s): Kaiser, Brent (Professor)

A structural view and understanding of NPF (nitrate transport) protein activity in maize

This PhD project will develop and analyse high quality crystallised proteins of the nitrate/chloride transport proteins ZmNPF6;4, ZmNPF6;4 (Y370H) and ZmNPF6;6. The goal will be to more...

Supervisor(s): Kaiser, Brent (Professor)

Dissecting the architecture of the Insulin Signaling Pathway

The aim of this pathway is to understand how the insulin signalling pathway regulates metabolic homeostasis.The Lead Supervisor for this project is David James. This project will a more...

Supervisor(s): James, David (Professor)

Novel drug development for human eye cancers

M. Phil or PhD project is available in this laboratory to discover and develop new drug candidates in treating human eye cancers.  more...

Supervisor(s): Zhou, Fanfan (Dr)

Targeting Rab7 and TBC1D15 to overcome mitochondrial dysfunction in neurological diseases

Pharmacological manipulation of contacts between mitochondria and LE/Lys could provide opportunities to improve PD, CMT2B and NPC disease. Virtual screening of compound libraries wi more...

Supervisor(s): Grewal , Thomas (Associate Professor), Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)