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UNDERSTANDING GENETIC VARIATIONS IN BONE

Functional genomics is a field that is undergoing major changes in practice due to the accessibility of gene editing technologies. Our team has developed methods for gene editing in more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

GENE THERAPY FOR GENETIC BONE DISEASES

Gene therapy is becoming a practical approach to treat severe genetic conditions and in recent years conditions such as Spinal Muscular Atrophy (SMA) have been success stories. Our more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

Genetics of Healthy Ageing

By exploiting the vast genetic landscape of an outbred mouse population we aim to explore the molecular cause of a range of diseases that limit healthy ageing in humans. This includ more...

Supervisor(s): James, David (Professor)

Creating new synthetic biology tools for genome engineering in bacteria

The new discipline of synthetic biology (SynBio) promises to transform every aspect of our lives, from medicines to agriculture to industry. The vision of SynBio is that organisms c more...

Supervisor(s): Coleman, Nicholas (Associate Professor)

Discovering biomarkers for mental disorders with neuroimaging

The opportunity studies brain structural and functional architecture in healthy and disordered brain with neuroimaging, and uses the novel knowledge gained to improve the diagnosis more...

Supervisor(s): Lv, Jinglei (Dr)

Evolutionary impacts of Tasmanian devil population restoration

Tasmanian devils are in decline due to devil facial tumour disease (DFTD), so the Save the Tasmanian Devil Program has been using translocations to help restore wild populations and more...

Supervisor(s): Grueber, Catherine (Dr)

Green Chemistry - Biocatalysis For Production Of High-Value Chemicals

The ultimate aim of biocatalysis research is to replace the petrochemical industry with clean and green microbial reactions using renewable and non-toxic feedstocks. But how exactly more...

Supervisor(s): Coleman, Nicholas (Associate Professor), Rutledge, Peter (Professor)

Multi-omic responses to dietary change: insights from poultry

Diet is a crucial mechanism by which organisms interact with their environment. The body responds to the food it receives to control nutrient uptake and moderate physiological pathw more...

Supervisor(s): Grueber, Catherine (Dr), Liu, Sonia (Dr), Whittington, Camilla (Dr)

Ethylene-oxidising bacteria as novel tools for agriculture

The 'fast-growing' species of mycobacteria are common in many environments and known to be important for the biodegradation of pollutants, but the biology of this fascinating group more...

Supervisor(s): Coleman, Nicholas (Associate Professor)

PRECLINICAL AND CLINICAL DEVELOPMENT OF NOVEL BONE-BINDING ANTIMICROBIALS

Our team has spent several years developing and testing new a new class of drugs termed bone-binding antimicrobials (BBAs). Our lead compound (BBA-1) has been shown to have antimicr more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor)