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Gene editing of stem cells or cancer to develop new stem cell therapies to treat human disease

This project involves the use of human stem cells and CRISPR genome editing to study basic signalling pathways controlling stem cell differentiation and/or cancer. A compliment more...

Supervisor(s): Neely, Greg (Associate Professor)

Imaging atherogenesis in a zebrafish model

This project will characterise immune cell dynamics during atherogenesis by live imaging, and investigate the importance of vascular remodelling and leakage in fuelling atheroma pat more...

Supervisor(s): Oehlers, Stefan (Dr), Britton, Warwick J (Professor)

Biomolecular studies of Parkinson’s disease

Opportunities exist to join a leading group conducting research into Parkinson's disease. Our group combines the disciplines of biochemistry, immunology, molecular biology and cell more...

Supervisor(s): Dzamko, Nicolas (Dr)

Vascular dysfunction in mycobacterial pathogenesis

This project will investigate the importance of vascular remodelling and leakage in fuelling tuberculosis infection more...

Supervisor(s): Oehlers, Stefan (Dr), Britton, Warwick J (Professor)

Molecular insights into a novel mammalian oxygen-sensing pathway

Oxygen (O2) is a vital biological resource most prominently known for its role as the final electron acceptor in aerobic respiration and, as such, adequate molecular mechanisms are more...

Supervisor(s): White, Mark (Dr), Mackay, Joel (Professor)

Design of Novel Biosensors and Microfluidic Devices for Interrogating the Insulin Signalling Pathway

The aim of this project is to design, engineer and validate novel biosensors that can be used to interrogate the insulin signalling pathway in live cells. more...

Supervisor(s): James, David (Professor)

Defining the clinical and immunogenetic profile in antibody-associated demyelination

Masters or PhD opportunity ideally suited for a medical or neurology trainee or fellow with a commitment to building expertise in clinical and translational neuroimmunology. more...

Supervisor(s): Ramanathan, Sudarshini (Dr), Brilot-Turville, Fabienne (Dr), Dale, Russell (Professor)

Regulation of Lipid Turnover in the body

The project involves characterisation of a novel lipolysis regulator in adipocytes. more...

Supervisor(s): James, David (Professor)

The role of redox in signalling: assessing the requirement of reactive oxygen species in signal transduction

Define the role of ROS in insulin signal transduction and explore how loss of control of this process causes diseases such as diabetes and cancer more...

Supervisor(s): James, David (Professor)

Pain Phenotype Characterisation in Preclinical Models of Osteoarthritis

Osteoarthritis (OA) is the most common chronic joint disease, affecting 15% of the population and causing a significant socioeconomic burden. It is a debilitating condition characte more...

Supervisor(s): Zaki, Sanaa (Dr)