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Creating new synthetic biology tools for genome engineering in bacteria

The new discipline of synthetic biology (SynBio) promises to transform every aspect of our lives, from medicines to agriculture to industry. The vision of SynBio is that organisms c more...

Supervisor(s): Coleman, Nicholas (Associate Professor)

Molecular Mechanism of Insulin Resistance

Insulin resistance is a major physiological problem that is associated with an inability of insulin to regulate glucose and lipid metabolism. We now know that metabolism is central more...

Supervisor(s): James, David (Professor)

Developing new antibiotics by targeting specific molecular interactions in bacteria

This project focuses on developing a new class of antibiotics by targeting specific molecular interactions in bacteria using a multi-disciplinary fragment-based drug design approach more...

Supervisor(s): Kwan, Ann (Dr)

Green Chemistry - Biocatalysis For Production Of High-Value Chemicals

The ultimate aim of biocatalysis research is to replace the petrochemical industry with clean and green microbial reactions using renewable and non-toxic feedstocks. But how exactly more...

Supervisor(s): Coleman, Nicholas (Associate Professor), Rutledge, Peter (Professor)

Ethylene-oxidising bacteria as novel tools for agriculture

The 'fast-growing' species of mycobacteria are common in many environments and known to be important for the biodegradation of pollutants, but the biology of this fascinating group more...

Supervisor(s): Coleman, Nicholas (Associate Professor)

Evolutionary impacts of Tasmanian devil population restoration

Tasmanian devils are in decline due to devil facial tumour disease (DFTD), so the Save the Tasmanian Devil Program has been using translocations to help restore wild populations and more...

Supervisor(s): Grueber, Catherine (Dr)

Role of Protein Phosphorylation in Cellular Function

Using advances in mass spectrometry-based proteomics this project aims to uncover how phosphorylation affects the function of proteins and cells in both healthy and diseased states. more...

Supervisor(s): James, David (Professor)

Genetics of Healthy Ageing

By exploiting the vast genetic landscape of an outbred mouse population we aim to explore the molecular cause of a range of diseases that limit healthy ageing in humans. This includ more...

Supervisor(s): James, David (Professor)

Using metabolomics and other omics to guide new cancer therapies

This project will investigate cellular status and signaling in novel cancer therapies, especially new irradiation schemes in radiotherapy using metabolomics, transcriptomics and pro more...

Supervisor(s): Kwan, Ann (Dr), McKenzie, David (Professor)

Multi-omic responses to dietary change: insights from poultry

Diet is a crucial mechanism by which organisms interact with their environment. The body responds to the food it receives to control nutrient uptake and moderate physiological pathw more...

Supervisor(s): Grueber, Catherine (Dr), Liu, Sonia (Dr), Whittington, Camilla (Dr)