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Investigation of the role of microRNAs in cell differentiation

Investigating the role of microRNAs in the regulation of stem cell multipotency and differentiation. more...

Supervisor(s): Rasko, John (Professor)

GENES AND CELL-CELL INTERACTIONS IN CANCER PROGRESSION..

Oncogenes, tumour suppressor genes and cell-cell interactions in cancer: which are important in driving tumour progression and invasion in squamous cell carcinomas? more...

Supervisor(s): Lyons, Guy (Associate Professor)

Regulatory Proteins in Development and Disease

PhD projects in this laboratory are focused on understanding how key proteins can lead to both normal development and disease, and using this knowledge to develop reagents to inhibi more...

Supervisor(s): Matthews, Jacqueline (Professor)

Understanding ageing of the endothelium

The investigations are focussed on identifying the biological and molecular changes that occur when endothelial cells undergo senescence (ageing) and the impact on disease such as d more...

Supervisor(s): Gamble, Jennifer (Professor)

Genetic control of resistance and susceptibility to tuberculosis

Both environmental and genetic factors influence susceptibility to tuberculosis; this project will identify and investigate polymorphisms in genes that may increase susceptibility t more...

Supervisor(s): Saunders, Bernadette (Dr)

Protein and peptide biomarkers of myocardial ischemia

This project will identify novel biomarkers (diagnostics) of ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

The role of calcium overload in myocardial ischemia / reperfusion injury

This project aims to identify the biochemical targets of calcium overload responsible for ischemia / reperfusion injury in the heart. more...

Supervisor(s): Cordwell, Stuart (Professor)

Identification of proteins specific to transmissible Pseudomonas aeruginosa in cystic fibrosis infection

This project will characterize the molecular basis for increased infectivity caused by an epidemic strain of Pseudomonas aeruginosa (AES-1) which infects many patients treated in cy more...

Supervisor(s): Cordwell, Stuart (Professor)

Post-translational modifications in bacterial proteins

This project will identify novel proteins that are post-translationally modified in bacterial pathogens and the role of such modification in virulence. more...

Supervisor(s): Cordwell, Stuart (Professor)

Unravelling mechanisms determining the balance between tolerance and immunity in the liver

Role of primary T cell activation in the liver in CD8 T cell tolerance more...

Supervisor(s): Bertolino, Patrick (Dr)