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Gene editing of stem cells or cancer to develop new stem cell therapies to treat human disease

This project involves the use of human stem cells and CRISPR genome editing to study basic signalling pathways controlling stem cell differentiation and/or cancer. A compliment more...

Supervisor(s): Neely, Greg (Professor)

Brain Cancer and Hypoxia

Aggressive brain tumours, including adult glioblastomas and pediatric DIPGs, are difficult to treat. Survival rates have improved very little over the last 30 years indicating a nee more...

Supervisor(s): Cook, Kristina (Dr)

The anti-apoptotic activity of serum albumin for endothelial cells

Earlier work in my laboratory, established that serum albumin contains a cryptic protein domain that is exposed through transient intra-molecular protein movement, to bind a G-prote more...

Supervisor(s): Zoellner, Hans (Professor)

Studies in Cell-Projection Pumping

Cell-projection pumping (CPP) is a mechanism we have recently discovered whereby cells pump cytoplasm between each other. We have discovered this in context of cancer, where there i more...

Supervisor(s): Zoellner, Hans (Professor)

Gene function and RNA processing in gut endoderm development

This project aims to unravel the impact of RNA processing on the function the targets of a RNA binding protein in the development of the embryonic gut and the associated organs. more...

Supervisor(s): Fossat, Nicolas (Dr), Tam, Patrick (Professor)

Studies in the biophysics of dentine and dental caries

Although dental caries remains the world's most common infectious disease, current concepts of caries pathogenesis are based on microscopic methods now many decades old. Treatment w more...

Supervisor(s): Zoellner, Hans (Professor)

Dental robotics

Robotic dental surgery offers significant clinical advantages, but has not yet been developed. We are exploring development of dental robotics in collaboration with the Faculty of E more...

Supervisor(s): Zoellner, Hans (Professor)