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Targeting melanoma secretory pathways.

Cancer cells secrete a variety of factors that induce tumour growth, metastasis, angiogenesis, and alter the tumour stroma to create a more favourable microenviroment. This project more...

Supervisor(s): Weninger , Wolfgang (Professor), Beaumont, Kimberley (Dr)

MicroRNAs in disease

Regulation of the endothelial cell barrier integrity is critical in inducing new blood vessel formation (angiogenesis), in developing an inflammatory response and importantly in res more...

Supervisor(s): Gamble, Jennifer (Professor)

Combined, Correlative and Integrated Microscopy: Unraveling Biomolecular Structure-Function Activities in Cancer & Transendothelial Transport

Our team seek to understand the spatial and temporal mechanisms involved in the onset and progress of colorectal cancer by using state-of-the-art multidimensional microscopy and 3-D more...

Supervisor(s): Braet, Filip (Associate Professor)

Fluorescent sensors for oxidative stress

Oxidative stress is associated with all diseases of ageing, and there is therefore a need for better tools to identify and quantify the condition. We are developing novel fluorescen more...

Supervisor(s): New, Elizabeth (Associate Professor)

Gadolinium complexes as new theranostic agents for brain cancer

The 5-year survival rate for patients afflicted with aggressive and intractable brain tumours (gliomas) is less than 4%.  In this project, we will incorporate Gd3+ ions into mi more...

Supervisor(s): Rendina, Louis (Professor)

Neuroscience/Neuroimmunology Research: Role of antibody in brain immune-mediated diseases

The Institute of Neuromuscular Research (INMR) is part of the Children's Hospital at Westmead (CHW), the largest paediatric centre in NSW, providing the most advanced care and treat more...

Supervisor(s): Brilot-Turville, Fabienne (Dr), Dale, Russell (Professor)

Understanding the role of novel genes in disease

From mRNA arrays we have identified a number of ‘novel’ genes that influence tissue function. Our studies are investigating the biochemical basis for the mechanism of ac more...

Supervisor(s): Gamble, Jennifer (Professor)

Mitochondial DNA damage, potential target to reduce the development of renal disorders induced by maternal smoking .

Smoking rates are disproportionately high in disadvantaged populations, particularly in emerging economies, and increasing in women of child bearing age. more...

Supervisor(s): Saad, Sonia (Dr)

Catalysis of Sustainable Processes

Available projects involve the development of novel catalysts for the generation of hydrogen by splitting water with sunlight, for biomass conversion, for green industrial oxidation more...

Supervisor(s): Masters, Tony (Associate Professor)

Protecting the heart from ischaemia-reperfusion injury: a new role for FXYD proteins?

We are interested to have a PhD student join our team at the Kolling Institute, examining the therapeutic potential of FXYD proteins in a model of heart attack/myocardial infarction more...

Supervisor(s): Figtree, Gemma (Associate Professor)