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Computational Modeling of Immune Cell Chemotaxis and Swarming

 Using computational simulation to form and evaluate hypotheses concerning the factors that drive immune cell motility, such as neutrophil swarming, during inflammation. more...

Supervisor(s): Read, Mark (Dr)

Computational characterisation of trans-regulatory cell systems

This project aims provide enabling computational and statistical methods for characterising trans-regulatory networks in cell systems. The goal is to discover regulatory networks th more...

Supervisor(s): Yang, Pengyi (Dr)

Computational approaches to elucidate Multiple Sclerosis and Contact Dermatitis pathogenesis, and its treatment through ultraviolet light exposure

Allergies and autoimmunity are complex immune system aberrations. Both involve multiple immune cell populations coordinating across several organs of the body. The growing prevalenc more...

Supervisor(s): Read, Mark (Dr)

ENGINEERED EXTRASYNAPTIC GABAA RECEPTORS: TOWARDS NOVEL ANALGESICS

Recently, there has been an increase of interest in α4δ-containing GABAA receptors as novel drug targets for the design of a new class of analgesics. However, to date th more...

Supervisor(s): Balle, Thomas (Associate Professor), Collins, Mary (Professor)

Reconstruct trans-regulatory networks using multi-omics profiling and data integration

A major initiative in our group is to integrate trans-omics datasets generated by a state‐of‐the‐art mass spectrometer (MS) and next-generation sequencer (NGS) from various ce more...

Supervisor(s): Yang, Pengyi (Dr)

Emergence of universal coding in evolutionary dynamics

The research will involve theoretical work in information theory as well as computer simulations. It will investigate complex systems approaches to one of the most fundamental probl more...

Supervisor(s): Prokopenko , Mikhail (Professor)

Respiratory syncytial virus in Australia: Molecular Epidemiology and Evolution

This project aims to better understand the molecular epidemiology and evolution of respiratory syncytial virus (RSV) in Australia using whole-genome sequencing and phylogenetic appr more...

Supervisor(s): Eden, John-Sebastian (Dr)

Feature-Centric Content Analysis for Bioimaging Informatics

This study aims to develop novel algorithms for content analysis in microscopic images, such as segmentation of cell nuclei, detection of certain cell structures, and tracing of cel more...

Supervisor(s): Cai, Tom Weidong (Associate Professor)

Neuromorphic AI

This project involves complex systems modelling of neuromorphic atomic switch networks to emulate emergent brain-like features of adaptive, deep-learning for application to Artifici more...

Supervisor(s): Kuncic, Zdenka (Professor)

Mining genomic data to understand diseases

In this project, we aim to develop, apply ,and enhance bioinformatics and statistical tools to effectively collate, query, and mine public data repositories of transcription factor more...

Supervisor(s): Khushi, Matloob (Dr)