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Amino acid sensing mechanisms in human biology.

Amino acid sensing mechanisms determine how dietary protein regulates appetite and satiety, how feeding influences endocrine responses and how nutrition can direct cell fate in brea more...

Supervisor(s): Conigrave, Arthur (Professor)

Understanding how Flaviviruses interact with the host immune system to cause disease

This laboratory is investigating the interaction of neurotropic Flaviviruses with the vertebrate host immune system to discover how it causes immune-mediated disease (immunopatholog more...

Supervisor(s): King, Nicholas (Professor)

Stem Cells in Liver Disease

The role of stem cells in progressive liver injury. more...

Supervisor(s): Shackel, Nicholas (Dr)

Regulation of ion transport in the respiratory epithelium in health and disease

The project will focus on elucidating the mechanisms by which respiratory pathogens including influenza, parainfluenza, avian influenza (H5N1) viruses, and microbacterium tuberculos more...

Supervisor(s): Cook, David I (Professor)

The Role of Extracellular Matrix Metalloprotease Inducer (EMMPRIN) in Liver Disease

The role of the hepatocyte in progressive liver injury. more...

Supervisor(s): Shackel, Nicholas (Dr)

Detecting smokers at risk of developing COPD

The applicant's research will be focussed on improving the understanding of underlying pathophysiology and the nature of early smoking related abnormalities in chronic obstructive p more...

Supervisor(s): King, Gregory (Associate Professor), Thamrin, Cindy (Dr)

Proteomic Mapping and Molecular Modelling of Avian H5N1 Influenza Antigen Epitopes Targeted by Human Antibodies

In studying Avian H5N1 Influenza specific Antibodies within Humans the aim is to clearly and definitively identify the respective viral proteins and epitopes targeted by neutralizin more...

Supervisor(s): Lynch, Garry (Dr)

Interplay between Innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection

This study is to investigate the link between innate and adaptive immunity in kidney ischemia reperfusion injury and allograft rejection with a view to identifying new therapeutic t more...

Supervisor(s): Chadban, Steve (Professor), Wu, Huiling (Associate Professor)

A Novel Approach of Inhibiting Pancreatic Cancer Metastasis via Targeting Tumour Micro-Environment Induced Autophagy

Targeting autophagy and metastasis in pancreatic cancer via NDRG1 Pancreatic Cancer (PC) is highly metastatic with the highest mortality of all cancers (~93%). The pancreatic tu more...

Supervisor(s): Sahni, Sumit (Dr)

The transformation of normal melanocytes into melanoma

This project investigates the role of the oncogenes Ras and Braf and the tumour suppressors p16INK4a, p14ARF, p53 and PTEN in the malignant transformation of melanocytes. more...

Supervisor(s): Kefford, Richard (Professor)