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Understanding the Switch between Enzyme and Signaling Behaviours in Human Group IIA Secreted Phospholipase A2 by Inhibitory Intervention

The principles of soluble protein structure and ligand docking are applied to structure analysis of membrane bound protein receptors and receptor ligand complexes. more...

Supervisor(s): Church, W Bret (Dr)

Develop single-cell mechanobiological methods for discovering molecular mechanisms of cardiovascular and neuronal mechanical force sensing

We are developing cutting-edge technologies for the following biomedical application: 1) define the mechanosensing functions of key protein players in the cardiovascular system such more...

Supervisor(s): Ju, Lining (Arnold) (Dr)

Protecting the heart from ischaemia-reperfusion injury: a new role for FXYD proteins?

We are interested to have a PhD student join our team at the Kolling Institute, examining the therapeutic potential of FXYD proteins in a model of heart attack/myocardial infarction more...

Supervisor(s): Figtree, Gemma (Associate Professor)

Light-harvesting complexes: adaptation and efficiency

Different light-harvesting strategy and flexible regulatory mechanism for maximising light-energy capture and their potential application for increasing the biomass and crop product more...

Supervisor(s): Chen, Min (Professor)

Molecular mechanism of photo-regulation in cyanobacteria

Red-light perception and red-shifted chlorophylls: evolutionary consequences. The importance of red light is highlighted by the diversity of photoreceptors and the potential enhance more...

Supervisor(s): Chen, Min (Professor)

A New Therapeutic Strategy to Overcome Multidrug Resistance by Exploiting Drug-Transporters to Target Untreatable Cancers

We recently have discovered a frontier strategy for overcoming drug resistance mediated by P-glycoprotein (Pgp) in the lysosome. Identifying new targets for resistant cancers are cr more...

Supervisor(s): Jansson, Patric (Dr)

Cyanobaterial photoregulatory mechanisms, pigmentation varieties and their evolutionary significance

The red-shifted chlorophylls contain an extra formyl group compared to chlorophyll a in cyanobacteria. The oxygen atom in the formyl group requires oxygen molecules as one important more...

Supervisor(s): Chen, Min (Professor)

Prevention of cardiac side effects of cancer treatment

This project will investigate a novel drug combination therapy that has potential benefits in cancer treatment induced heart failure by targeting Na+-K+ pump function. more...

Supervisor(s): Liu, Chia-chi (Dr), Ramussen, Helge (Professor)

Solute Carrier Transporters

PhD project is available in this laboratory on investigating the relationship of human drug transporters with drugs in treating prevalent diseases such as diabetes and cancers. more...

Supervisor(s): Zhou, Fanfan (Dr)