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Synaptic signalling therapies for anti-acetylcholine receptor myasthenia gravis

This project will use a mouse model to test potential treatments for the autoimmune disease, anti-acetylcholine receptor myasthenia gravis. more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

Significance of Osteopontin and its splice variants in alcoholic liver disease

Alcohol induced Opn and Opn isoforms play a role in the progression of alcoholic liver injury mediated via integrin and non-integrin receptor binding. more...

Supervisor(s): Seth, Devanshi (Dr)

Prostate cancer metabolism – investigating the role of lipid metabolism and the microenvironment

This project aims to investigate potential interaction the different cell types near the prostate gland and how changes in androgen signalling alters this relationship. It also aims more...

Supervisor(s): Hoy, Andrew (Dr)

Precoded multiuser MIMO and packet scheduling

Linear precoding for multiuser Multiple-Input Multiple-Output (MIMO) systems has attracted much attention recently due to the capacity enhancement ability at the system level. In th more...

Supervisor(s): Vucetic, Branka (Professor), Lin, Zihuai (Dr)

A novel drug combination therapy for heart failure

This project will investigate a novel drug combination therapy that has potential benefits in heart failure treatment by targeting Na+-K+ pump function. more...

Supervisor(s): Ramussen, Helge (Professor)

Glucocorticoid effects on bone: The role of the osteoblast

 Glucocorticoid effects on bone: The role of the osteoblast more...

Supervisor(s): Seibel, Markus (Professor), Zhou, Hong (Professor)

Conopeptides as potential pain therapeutics

Dissecting mechanisms of chronic pain using patch clamp analyses of cellular and synaptic electrophysiology in spinal cord slices and behavioural correlations. more...

Supervisor(s): Christie, Macdonald (Professor)

The Role of PPAR gamma in thyroid cancer

Differentiation therapy for thyroid cancer by targeting the fusion gene PAX8-PPARgamma. more...

Supervisor(s): Clifton-Bligh, Roderick (Dr)

A cell culture model for Muscle Specific Kinase myasthenia gravis

The postsynaptic membrane of the neuromuscular junction (NMJ) is organized by Muscle specific tyrosine kinase (MuSK). This project will investigate the mechanisms that organize the more...

Supervisor(s): Phillips, William (Bill) (Associate Professor)

A Novel Approach of Inhibiting Pancreatic Cancer Metastasis via Targeting Tumour Micro-Environment Induced Autophagy

Targeting autophagy and metastasis in pancreatic cancer via NDRG1 Pancreatic Cancer (PC) is highly metastatic with the highest mortality of all cancers (~93%). The pancreatic tu more...

Supervisor(s): Sahni, Sumit (Dr)