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Regulation of stem cell behaviour using functional biomolecules

Investigate and develop new ways of manipulating different aspects of stem cell behaviour.  This knowledge paves the way towards understanding their fundamental biology and cre more...

Supervisor(s): Yeo, Giselle (Dr)

Gene editing of stem cells or cancer to develop new stem cell therapies to treat human disease

This project involves the use of human stem cells and CRISPR genome editing to study basic signalling pathways controlling stem cell differentiation and/or cancer. A compliment more...

Supervisor(s): Neely, Greg (Professor)

Studies in Cell-Projection Pumping

Cell-projection pumping (CPP) is a mechanism we have recently discovered whereby cells pump cytoplasm between each other. We have discovered this in context of cancer, where there i more...

Supervisor(s): Zoellner, Hans (Professor)

Machine learning in cell identity, fate decision, and lineage prediction

Multi-omics and single-cell omics approaches are transforming our understanding of stem cell-based regeneration of tissues and organs on the individual cell level. By generating and more...

Supervisor(s): Yang, Pengyi (Dr)

Computational characterisation of trans-regulatory cell systems

This project aims provide enabling computational and statistical methods for characterising trans-regulatory networks in cell systems. The goal is to discover regulatory networks th more...

Supervisor(s): Yang, Pengyi (Dr)

Facilitating treatments for neurodegenerative Parkinson’s disease

Opportunities exist to join a leading group conducting research into Parkinson's disease. Our group combines the disciplines of biochemistry, immunology, molecular biology and cell more...

Supervisor(s): Dzamko, Nicolas (Dr)

Reconstruct trans-regulatory networks using multi-omics profiling and data integration

A major initiative in our group is to integrate trans-omics datasets generated by a state‐of‐the‐art mass spectrometer (MS) and next-generation sequencer (NGS) from various ce more...

Supervisor(s): Yang, Pengyi (Dr)

The anti-apoptotic activity of serum albumin for endothelial cells

Earlier work in my laboratory, established that serum albumin contains a cryptic protein domain that is exposed through transient intra-molecular protein movement, to bind a G-prote more...

Supervisor(s): Zoellner, Hans (Professor)

CRISPR-based genome editing

The recent development of genome editing technology is perhaps the single biggest technical breakthrough in the history of life sciences, allowing for near complete control over euk more...

Supervisor(s): Neely, Greg (Professor)

Studies in the biophysics of dentine and dental caries

Although dental caries remains the world's most common infectious disease, current concepts of caries pathogenesis are based on microscopic methods now many decades old. Treatment w more...

Supervisor(s): Zoellner, Hans (Professor)