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Role of Protein Phosphorylation in Cellular Function

Using advances in mass spectrometry-based proteomics this project aims to uncover how phosphorylation affects the function of proteins and cells in both healthy and diseased states. more...

Supervisor(s): James, David (Professor)

Targeting Rab7 and TBC1D15 to overcome mitochondrial dysfunction in neurological diseases

Pharmacological manipulation of contacts between mitochondria and LE/Lys could provide opportunities to improve PD, CMT2B and NPC disease. Virtual screening of compound libraries wi more...

Supervisor(s): Grewal , Thomas (Associate Professor), Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

Dissecting the architecture of the Insulin Signaling Pathway

The aim of this pathway is to understand how the insulin signalling pathway regulates metabolic homeostasis.The Lead Supervisor for this project is David James. This project will a more...

Supervisor(s): James, David (Professor)