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Targeting Rab7 and TBC1D15 to overcome mitochondrial dysfunction in neurological diseases

Pharmacological manipulation of contacts between mitochondria and LE/Lys could provide opportunities to improve PD, CMT2B and NPC disease. Virtual screening of compound libraries wi more...

Supervisor(s): Grewal , Thomas (Associate Professor), Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

Artificial Intelligence in Ion Channel Drug Discovery

Application of machine learning and artificial intelligence methods to develop models predictive of drug activity, selectivity, stability and distribution. The project will be condu more...

Supervisor(s): Balle, Thomas (Associate Professor)

Fluorescent Tools for Super-resolution Imaging

This PhD project will involve the synthesis and characterization of innovative fluorescent sensors for specific amyloid proteins implicated in neurodegenerative disorders. The devel more...

Supervisor(s): Kaur, Amandeep (Dr), Sunde, Margaret (Associate Professor)

Using metabolomics and other omics to guide new cancer therapies

This project will investigate cellular status and signaling in novel cancer therapies, especially new irradiation schemes in radiotherapy using metabolomics, transcriptomics and pro more...

Supervisor(s): Kwan, Ann (Dr), McKenzie, David (Professor)

Developing new antibiotics by targeting specific molecular interactions in bacteria

This project focuses on developing a new class of antibiotics by targeting specific molecular interactions in bacteria using a multi-disciplinary fragment-based drug design approach more...

Supervisor(s): Kwan, Ann (Dr)

Uncovering the source of CO2 that’s respired when dry soil is rewet

Soil respiration is one of the largest components of the global C cycle, but also one of the hardest to model. A key aspect of this difficulty is that we do not have a good mechanis more...

Supervisor(s): Warren, Charles (Associate Professor)

Dental robotics

Robotic dental surgery offers significant clinical advantages, but has not yet been developed. We are exploring development of dental robotics in collaboration with the Faculty of E more...

Supervisor(s): Zoellner, Hans (Professor)