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Atomic structure, assembly, interactions and engineering of functional amyloids

This project aims to engineer hydrophobins for a range of biotechnological applications from coating of medical implants to formulation of drug delivery vehicles. The work includes more...

Supervisor(s): Kwan, Ann (Dr)

STUDIES OF VARIABLE OR CONSERVED SURFACE PROTEIN SITES OF NEISSERIA MENINGITIDIS AS EPITOPES FOR STRAIN-SPECIFIC VACCINES OR BROAD-STRAIN (UNIVERSAL) VACCINES

The gram-negative Neisseria Meningititis (NM) remains a significant microbial problem and particularly lethal for the very young. Serogroup B strains are particularly troublesome an more...

Supervisor(s): Lynch, Garry (Dr)

ASSESS THE GP GLYCOPROTEIN STRUCTURES OF EBOLA AND MARBURG VIRUS ENVELOPES, THEIR MUCIN-LIKE DOMAINS AND SITES FOR IMMUNE ATTACK

This project extends our published ebola (EBOV) gp's structures, and furthers our studies for immune targeting. Taking a holistic approach our studies aim to examine both the standa more...

Supervisor(s): Lynch, Garry (Dr)

The HAMLET molecular species with anticancer properties

We are interested to determine how the anti-cancer properties of this family of molecules can be translated into cancer treatment. We believe there may be a delivery system which n more...

Supervisor(s): Church, W Bret (Dr)

ENGINEERED EXTRASYNAPTIC GABAA RECEPTORS: TOWARDS NOVEL ANALGESICS

Recently, there has been an increase of interest in α4δ-containing GABAA receptors as novel drug targets for the design of a new class of analgesics. However, to date th more...

Supervisor(s): Balle, Thomas (Associate Professor), Collins, Mary (Professor)

Developing Novel Biotherapeutics and Vaccines

We are looking for an enthusiastic and motivated candidate who has a background in pharmacy, chemistry, chemical engineering or an allied subject to work on the development, synthes more...

Supervisor(s): Kayser, Veysel (Associate Professor)

PET imaging of glioma in a TSPO knockout model

Glioblastoma is the most frequent primary brain tumour and the most malignant glial neoplasm (glioma) with predominantly astrocytic differentiation. Due to their invasive nature, gl more...

Supervisor(s): Graeber, Manuel (Professor), Banati, Richard (Professor)

Discovering DNA sequences based on error control codes

Error control codes have been widely used in communication systems to reduce errors in transmission. The general idea is that redundant symbols are first added to the useful data sy more...

Supervisor(s): Li, Yonghui (Professor), Vucetic, Branka (Professor)

Solute Carrier Transporters

PhD project is available in this laboratory on investigating the relationship of human drug transporters with drugs in treating prevalent diseases such as diabetes and cancers. more...

Supervisor(s): Zhou, Fanfan (Dr)

Using Gene editing to cure genetic neurological disorders

This project is an opportunity for a PhD student who is interested in genetic disorders of the brain and who is prepared to work at the cutting edge of technology. Genetic neurologi more...

Supervisor(s): Gold, Wendy (Dr)