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Head Development: Intersection of transcriptional and signalling activities

This project is designed to test the hypothesis that head formation during embryogenesis is controlled by a multitude of interacting transcriptional and signalling activities and t more...

Supervisor(s): Tam, Patrick (Professor), Fossat, Nicolas (Dr)

Taking proteomics to the clinic – biomarker and pathway analysis of patient samples

Only approximately 50% of patients will be successfully diagnosed by genetic analysis and even when a gene is identified, there may be no immediate drug target. Proteomics analysis more...

Supervisor(s): Graham, Mark (Dr)

Mouse models of liver cancer

This project will use mouse models to investigate the role of adiponectin and T-cadherin in models of liver cancer. more...

Supervisor(s): Hebbard, Lionel (Dr), Qiao, Liang (Dr)

A novel regulatory pathway affecting red cell and platelet phenotype

A novel mutation has been identified in an Australian family with a combined defect in platelet and red cell function. This project will explore the molecular mechanism of this defe more...

Supervisor(s): Ward, Chris (Professor)

A novel drug combination therapy for heart failure

This project will investigate a novel drug combination therapy that has potential benefits in heart failure treatment by targeting Na+-K+ pump function. more...

Supervisor(s): Ramussen, Helge (Professor)

Diseases of the Aorta

The causes of sporadic thoracic aortic aneurysms are not understood but the consequences of this disease can be catastrophic. We have developed an animal model of disease and this t more...

Supervisor(s): Gamble, Jennifer (Professor)

The Role of the Osteoblast in Mediating Glucocorticoid-Induced Metabolic Dysfunction

To investigate how glucocorticoid affect the regulation of glucose and lipid metabolism. more...

Supervisor(s): Zhou, Hong (Professor), Seibel, Markus (Professor)

Medicinal and Pharmaceutical Chemistry — Design, Synthesis and Testing of Novel Anti-Cancer Agents

Are you interested in applying your laboratory expertise to the development of new drugs for cancer and other diseases?  Become part of a multi-disciplinary team involved in dr more...

Supervisor(s): Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)

The role of endogenous glucocorticoids in osteoarthritis

This is ongoing project to define the role and mechanism of endogenous glucocorticoids in osteoarthritis. more...

Supervisor(s): Zhou, Hong (Professor), Seibel, Markus (Professor)