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Combined, Correlative and Integrated Microscopy: Unraveling Biomolecular Structure-Function Activities in Cancer & Transendothelial Transport

Our team seek to understand the spatial and temporal mechanisms involved in the onset and progress of colorectal cancer by using state-of-the-art multidimensional microscopy and 3-D more...

Supervisor(s): Braet, Filip (Associate Professor)

‘Magic Bullet’ Cancer Drugs and Antibiotics

We are building new kinds of cancer drugs and antibiotics: molecules that change their behaviour in the presence of their biological target, being chemically activated only when the more...

Supervisor(s): Rutledge, Peter (Professor)

Understanding the Switch between Enzyme and Signaling Behaviours in Human Group IIA Secreted Phospholipase A2 by Inhibitory Intervention

The principles of soluble protein structure and ligand docking are applied to structure analysis of membrane bound protein receptors and receptor ligand complexes. more...

Supervisor(s): Church, W Bret (Dr)

Self-Assembly and Self-Organization in Complex Distributed Systems

The aim of this project is use a range of algorithmic techniques (graph theoretic, game theoretic, information theoretic) to study and gain insight into the processes of self-assemb more...

Supervisor(s): Zomaya, Albert Y. (Professor), Vadas, Mathew (Professor)

RNA-based biomarkers to understand and predict disease progression

RNA-based biomarkers are becoming increasingly important due to their stability and sensitivity of detection. This project will use in vitro, in vivo and clinical sample analysis b more...

Supervisor(s): Hardikar, Anandwardhan (Associate Professor)

Parallel Stochastic Optimization Algorithms

This project is investigating the application of unorthodox optimization techniques such fuzzy logic, genetic algorithms, neural networks, simulated annealing, ant colonies, Tabu se more...

Supervisor(s): Zomaya, Albert Y. (Professor), Vadas, Mathew (Professor)

MicroRNAs as Regulators of Cellular Programs

This project involves modeling the role of transcription factors and miRNAs in the control of systems implicated in maintaining and regaining optimal health. more...

Supervisor(s): Zomaya, Albert Y. (Professor), Vadas, Mathew (Professor)

Resilience and distributed systems for a healthy society

This project aims to develop an understanding of the link between the nature of distributed systems and the resilience that underpins healthy future societies. more...

Supervisor(s): Zomaya, Albert Y. (Professor), Vadas, Mathew (Professor)

Biological metaphors and resilience

The project will seek inspiration from biological networks to optimize the resilience of public health systems. more...

Supervisor(s): Zomaya, Albert Y. (Professor), Vadas, Mathew (Professor)

Complex Networks and Performance

The project aims to develop a social network based model and operational constructs for exploring individual behaviour in relation to choice and personal health. more...

Supervisor(s): Zomaya, Albert Y. (Professor), Vadas, Mathew (Professor)