Your Search Results

Carboranes as unique boron frameworks in medicinal chemistry

Boron-based drugs are increasingly being investigated in many disease categories, with numerous pharmaceutical companies (e.g. GSK, Anacor, and Takeda) dramatically expanding their more...

Supervisor(s): Rendina, Louis (Professor)

‘Magic Bullet’ Cancer Drugs and Antibiotics

We are building new kinds of cancer drugs and antibiotics: molecules that change their behaviour in the presence of their biological target, being chemically activated only when the more...

Supervisor(s): Rutledge, Peter (Professor)

Gadolinium complexes as new theranostic agents for brain cancer

The 5-year survival rate for patients afflicted with aggressive and intractable brain tumours (gliomas) is less than 4%.  In this project, we will incorporate Gd3+ ions into mi more...

Supervisor(s): Rendina, Louis (Professor)

Expanding the scope of the Stetter reaction

Opportunities exist to build complex organic molecules using the organocatalytic Stetter reaction. more...

Supervisor(s): McErlean, Christopher (Associate Professor)

Why are Ionic Liquids Extraordinary Solvents?

The use of ionic liquids has exploded over the last decades as solvents for unusual or difficult chemical syntheses.  These liquids consist solely of ions and have melting poin more...

Supervisor(s): Warr, Gregory (Professor)

Glass smithing on the micro and nano scales

Dating as far back as 3500 years when the ancient Egyptians and Mesopotamians began glazing pottery, glass processing and “smithing” has evolved into many forms culminat more...

Supervisor(s): Canning, John (Honorary Professor)

Laboratory Exobiology: Prebiotic Environments in Ionic Liquids?

Life in the universe is widely presumed only to be viable in the ‘Goldilocks zone’ around a star, where liquid water is available.  Some have speculated that Titan more...

Supervisor(s): Warr, Gregory (Professor)

Metal Ion Sensors for Medicinal and Environmental Applications

Metal cations like Zn(II), Cu and K(I) play a raft of important signalling roles in our bodies; others such as Hg(II), Cd(II) and Pb(II) are toxic pollutants in the environment. more...

Supervisor(s): Rutledge, Peter (Professor), Canning, John (Honorary Professor)

Fluorescent sensors for oxidative stress

Oxidative stress is associated with all diseases of ageing, and there is therefore a need for better tools to identify and quantify the condition. We are developing novel fluorescen more...

Supervisor(s): New, Elizabeth (Associate Professor)

Development of novel anti-cancer metastasis agents derived from omega-3 fatty acid metabolites

At present we have no therapies that prevent cancer spread. In this project we will develop novel w-3 fatty acid epoxide analogues that inhibit tumour metastasis. These derivatives more...

Supervisor(s): Murray, Michael (Professor)