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Vascular dysfunction in mycobacterial pathogenesis

This project will investigate the importance of vascular remodelling and leakage in fuelling tuberculosis infection more...

Supervisor(s): Oehlers, Stefan (Dr), Britton, Warwick J (Professor)

Imaging atherogenesis in a zebrafish model

This project will characterise immune cell dynamics during atherogenesis by live imaging, and investigate the importance of vascular remodelling and leakage in fuelling atheroma pat more...

Supervisor(s): Oehlers, Stefan (Dr), Britton, Warwick J (Professor)

TARGETING THE BRAIN VASCULATURE AS A TREATMENT FOR CEREBRAL TYPE I INTERFERONOPATHIES

Abnormal blood vessels are feature of cerebral type I interferonopathies. Discover how the endothelial cells that line the brain’s blood vessels contribute to disease in patie more...

Supervisor(s): Hofer, Markus (Dr)

THE PATHOGENIC AND PROTECTIVE EFFECTS OF MICROGLIA IN CEREBRAL CYTOKINOPATHIES

Microglia are the primary immune cells of the brain and have the potential to both protect and contribute to neurological disease. Explore the molecular mechanisms that microglia us more...

Supervisor(s): Hofer, Markus (Dr)

HOW DIFFERENT CELL TYPES OF THE BRAIN CONTRIBUTE TO CEREBRAL CYTOKINOPATHIES

The brain consists of a large number of different cell types, including neurons, astrocytes, oligodendrocytes, microglia and endothelial cells. Discover how these different cell typ more...

Supervisor(s): Hofer, Markus (Dr)

Pain Phenotype Characterisation in Preclinical Models of Osteoarthritis

Osteoarthritis (OA) is the most common chronic joint disease, affecting 15% of the population and causing a significant socioeconomic burden. It is a debilitating condition characte more...

Supervisor(s): Zaki, Sanaa (Dr)

EFFECTS OF TYPE I INTERFERONS IN CHRONIC VIRAL INFECTIONS

When type I interferon signalling is impaired, infection with lymphocytic choriomeningitis virus results in chronic infection and dysfunctional CD8+ T cell function. Investigate how more...

Supervisor(s): Hofer, Markus (Dr)

Epidemiological investigation of Chronic Obstructive Pulmonary Disease (COPD) within the Australian Burden of Lung Disease (BOLD) study

Between 2006 and 2012 we conducted a series of cross-sectional studies to investigate the prevalence, risk factors and burden of COPD in Australian adults aged 40+ years. This Austr more...

Supervisor(s): Toelle, Brett (Dr)

Exploring how markers of brain structure and function relate to lifestyle factors and clinical trajectory in individuals ‘at risk’ for dementia

This study offers a unique and rare opportunity to work with the Healthy Brain Ageing Program at the Brain and Mind Centre. This one-of-a-kind clinic offer early diagnosis and inter more...

Supervisor(s): Duffy, Shantel (Dr)

The anti-apoptotic activity of serum albumin for endothelial cells

Earlier work in my laboratory, established that serum albumin contains a cryptic protein domain that is exposed through transient intra-molecular protein movement, to bind a G-prote more...

Supervisor(s): Zoellner, Hans (Professor)