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Mechanosensation in human erythrocytes: NMR and microscopy studies

We/you will explore the mechanistic basis of the autonomous movement of the plasma membrane of red blood cells, so called membrane flickering. Also, the molecular processes that und more...

Supervisor(s): Kuchel, Philip (Emeritus Professor)

A structural view and understanding of NPF (nitrate transport) protein activity in maize

This PhD project will develop and analyse high quality crystallised proteins of the nitrate/chloride transport proteins ZmNPF6;4, ZmNPF6;4 (Y370H) and ZmNPF6;6. The goal will be to more...

Supervisor(s): Kaiser, Brent (Professor)

Develop single-cell mechanobiological methods for discovering molecular mechanisms of cardiovascular and neuronal mechanical force sensing

We are developing cutting-edge technologies for the following biomedical application: 1) define the mechanosensing functions of key protein players in the cardiovascular system such more...

Supervisor(s): Ju, Lining (Arnold) (Dr)

Define regulatory control pathways delivering NPF (nitrate) and AMT (ammonium) transport activities across root types and cell profiles

We have previously identified the tissue expression patterns of ZmNPF6;6 and ZmNPF6;4 in maize root tips (Wen, Z., et al., The Plant Cell, 2017) and used qPCR as well as custom arra more...

Supervisor(s): Kaiser, Brent (Professor)

Design and synthesis of selective anion receptors to facilitate transmembrane anion transport in epithelial cells

CF is a recessive genetic condition that results from the dysregulation of anion transport through the cystic fibrosis transmembrane regulator anion channel in epithelial cell membr more...

Supervisor(s): Gale, Philip (Professor)

Studies in Cell-Projection Pumping

Cell-projection pumping (CPP) is a mechanism we have recently discovered whereby cells pump cytoplasm between each other. We have discovered this in context of cancer, where there i more...

Supervisor(s): Zoellner, Hans (Professor)

Develop single-molecule and super-resolution microscopy imaging technologies in the cardiovascular disease

This project will focus on development, improvement, and application of single-molecule tracking and super-resolution imaging, such as TIRF, HiLo, PALM, STORM, Lattice Light-Sheet M more...

Supervisor(s): Ju, Lining (Arnold) (Dr)

Evolution of viviparity in fish

My lab offers a range of opportunities to build on our research program examining the evolution of reproductive complexity in fish, especially seahorses and sharks. Please see our w more...

Supervisor(s): Whittington, Camilla (Dr), Murphy, Christopher R (Professor)

Defining the genetic link between nitrate and ammonium transport proteins and root architecture in Maize and Barley

We have previously tested two contrasting maize inbred lines on their inherent nitrate transport rates and respective responses to growth at low nitrogen supply. The lines were sele more...

Supervisor(s): Kaiser, Brent (Professor)

Novel drug development for human eye cancers

M. Phil or PhD project is available in this laboratory to discover and develop new drug candidates in treating human eye cancers.  more...

Supervisor(s): Zhou, Fanfan (Dr)