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Embryonic stem cells

Embryonic stem (ES) cells have the potential to differentiate into any cell type of the developing embryo and adult. For this reason they have proved invaluable in understanding the more...

Supervisor(s): Morris, Michael (Dr)

Regulation of host resistance and immune response to human pathogens

The laboratory of Immunology and Host Defense focuses on the immune mechanisms that regulate host resistance to pathogens of global importance. It currently offers multiple projects more...

Supervisor(s): Feng, Carl (Dr)

LDL-cholesterol controls the role of integrins in cancer cell migration

This project explores the role of LDL-cholesterol in integrin trafficking and signalling, which is relevant for cancer cell migration. more...

Supervisor(s): Grewal , Thomas (Associate Professor)

Metal Ion Sensors for Medicinal and Environmental Applications

Metal cations like Zn(II), Cu and K(I) play a raft of important signalling roles in our bodies; others such as Hg(II), Cd(II) and Pb(II) are toxic pollutants in the environment. more...

Supervisor(s): Rutledge, Peter (Professor), Canning, John (Honorary Professor)

Protecting the heart from ischaemia-reperfusion injury: a new role for FXYD proteins?

We are interested to have a PhD student join our team at the Kolling Institute, examining the therapeutic potential of FXYD proteins in a model of heart attack/myocardial infarction more...

Supervisor(s): Figtree, Gemma (Associate Professor)

Müller glial-neuronal-vascular interactions in retinal vascular diseases

Research projects in the Macular Research Group are focused on the cellular and molecular mechanisms of Müller glial-neuronal-vascular interactions in retinal diseases. The gro more...

Supervisor(s): Gillies, Mark (Professor), Shen, Weiyong (Dr)

The anatomy and physiology of the intertidal marine isopod Cirolana harfordi

The intertidal isopod is a remarkably successful scavenger and predator and yet almost nothing is known about its development, anatomy and physiology, so this animal presents a uniq more...

Supervisor(s): Thomson, Murray (Dr)

Understanding the role of novel genes in disease

From mRNA arrays we have identified a number of ‘novel’ genes that influence tissue function. Our studies are investigating the biochemical basis for the mechanism of ac more...

Supervisor(s): Gamble, Jennifer (Professor)

Understanding the Switch between Enzyme and Signaling Behaviours in Human Group IIA Secreted Phospholipase A2 by Inhibitory Intervention

The principles of soluble protein structure and ligand docking are applied to structure analysis of membrane bound protein receptors and receptor ligand complexes. more...

Supervisor(s): Church, W Bret (Dr)

The Renin-Angiotensin System and its Role in Neuroprotective Strategies in a Glaucoma Model

At present, the only treatment for glaucoma is intraocular pressure control. We know some people still get worse despite good pressure control. We have evidence that a system previo more...

Supervisor(s): White, Andrew (Dr)