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UNDERSTANDING GENETIC VARIATIONS IN BONE

Functional genomics is a field that is undergoing major changes in practice due to the accessibility of gene editing technologies. Our team has developed methods for gene editing in more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

MODELLING EFFECTS OF LIGHT ON THE CIRCADIAN RHYTHMS

This project aims to advance our understanding of the effects of light on the circadian rhythms and develop a detailed biophysical model of the circadian photoreceptor system that i more...

Supervisor(s): Postnova, Svetlana (Dr)

Migrant and Refugee Youths’ Sexual and Reproductive Health and Rights

The population of migrant and refugee youth in Greater Western Sydney is increasing exponentially each year. Little is understood about these young people's understanding of and ab more...

Supervisor(s): Hossain, Zakia (Dr)

Genetics of Healthy Ageing

By exploiting the vast genetic landscape of an outbred mouse population we aim to explore the molecular cause of a range of diseases that limit healthy ageing in humans. This includ more...

Supervisor(s): James, David (Professor)

Curing antibiotic resistance plasmid from Enterobacteriaceae

The project includes to understand the biology of antibiotic resistance plasmids and develop effective strategy to cure them more...

Supervisor(s): Kamruzzaman, Muhammad (Dr), Iredell, Jon (Professor)

GENE THERAPY FOR GENETIC BONE DISEASES

Gene therapy is becoming a practical approach to treat severe genetic conditions and in recent years conditions such as Spinal Muscular Atrophy (SMA) have been success stories. Our more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

PRECLINICAL AND CLINICAL DEVELOPMENT OF NOVEL BONE-BINDING ANTIMICROBIALS

Our team has spent several years developing and testing new a new class of drugs termed bone-binding antimicrobials (BBAs). Our lead compound (BBA-1) has been shown to have antimicr more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor)