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Molecular Mechanism of Insulin Resistance

Insulin resistance is a major physiological problem that is associated with an inability of insulin to regulate glucose and lipid metabolism. We now know that metabolism is central more...

Supervisor(s): James, David (Professor)

Insulin-mediated regulation of adipocyte lipolysis

Insulin, a hormone that is released after a meal, regulates many aspects of metabolism including a process called lipolysis that involves the release of fatty acids into the circula more...

Supervisor(s): James, David (Professor)

Dissecting the architecture of the Insulin Signaling Pathway

The aim of this pathway is to understand how the insulin signalling pathway regulates metabolic homeostasis.The Lead Supervisor for this project is David James. This project will a more...

Supervisor(s): James, David (Professor)

Chronic Hepatitis B: from virological concepts to cure

We are seeking passionate Ph.D. and Masters candidates to conduct a research project on understanding how hepatitis B virus persists in the liver to ultimately design a cure for chr more...

Supervisor(s): Tu, Thomas (Dr), Douglas, Mark W (Associate Professor)

CHARACTERISATION OF ERUSIOLIN - A NEW PEPTIDE HORMONE

In this project we aim to characterise the function of a new gut-derived peptide we have discovered in human plasma, named erusiolin, which we hypothesise plays a role in appetite r more...

Supervisor(s): Larance, Mark (Dr)

Brain Cancer and Hypoxia

Aggressive brain tumours, including adult glioblastomas and pediatric DIPGs, are difficult to treat. Survival rates have improved very little over the last 30 years indicating a nee more...

Supervisor(s): Cook, Kristina (Dr)

MODELLING EFFECTS OF LIGHT ON THE CIRCADIAN RHYTHMS

This project aims to advance our understanding of the effects of light on the circadian rhythms and develop a detailed biophysical model of the circadian photoreceptor system that i more...

Supervisor(s): Postnova, Svetlana (Dr)