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Influencing anti-inflammatory functions of monocytes by targeting the haemoglobin scavenger receptor CD163: possible role in the development of diabetes complications

This project addresses the problem of how causes of diabetes complications, specifically the effect of diabetes on the regulation of one of these anti-inflammatory cell surface prot more...

Supervisor(s): Min, Danqing (Dr), McLennan, Susan (Dr), Twigg, Stephen (Professor)

Predicting the future risk of chronic kidney disease in offspring of obese mothers with and without type 2 diabetes

Chronic kidney disease (CKD) is a major health burden driven mostly by obesity and type 2 diabetes mellitus. 1/3 of diabetic patients are at risk of CKD progression for unknown reas more...

Supervisor(s): Saad, Sonia (Dr), Pollock, Carol (Professor)

Solute Carrier Transporters

PhD project is available in this laboratory on investigating the relationship of human drug transporters with drugs in treating prevalent diseases such as diabetes and cancers. more...

Supervisor(s): Zhou, Fanfan (Dr)

Developing small molecules that enhance PCSK9/AnxA2 interaction to inhibit PCSK9 and elevate LDLR levels

Statins to decrease low density lipoprotein cholesterol (LDL-C) are a cornerstone to prevent and treat cardiovascular events. However, inadequate dose response, resistance, and seri more...

Supervisor(s): Grewal , Thomas (Associate Professor)

Immuno-metabolism of macrophages in inflammatory diseases

In metabolic organs like the liver and fat, macrophage infiltration plays a pivotal role in driving low-grade chronic inflammation that results in many of the consequences of obesi more...

Supervisor(s): George, Jacob (Professor)

Nutrient regulation of the stem cell compartment

Australia is among the countries with the fastest growing rates of overweight and obesity, which by 2025 will affect >70% of the population. Chronic diseases linked to obesity in more...

Supervisor(s): George, Jacob (Professor)

Pilot Study of Progressive Resistance Training for Sedentary Adults with Charcot-Marie-Tooth

This project is for a resistance training program in persons with Charcot-Marie-Tooth (CMT). CMT is the most frequently inherited peripheral neuropathy affecting around 1 in 2500 pe more...

Supervisor(s): Fornusek, Che (Dr)

Pilot Efficacy Trial of Electrical Stimulation Cycling Exercise for Advanced Multiple Sclerosis

Multiple sclerosis (MS) is an incurable disease of the central nervous system that typically affects people in their 30's and 40's. MS results in slowly increasing muscle paralysis, more...

Supervisor(s): Fornusek, Che (Dr)

Investigation of the Demands of Participation in Physical Disability Rugby League

Physical Disability Rugby League is a sport that was created in Sydney to allow persons with physical disability to play league (https://www.youtube.com/watch?v=yV04gbXUURo). Curren more...

Supervisor(s): Fornusek, Che (Dr)

James Millner PHD Scholarship in Pharmacy

James Millner AM graduated from Pharmacy at the University of Sydney in 1947 and after returning home from being a prisoner of war during World War 2, he joined the family business, more...

Supervisor(s): Bero , Lisa (Professor)