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Predicting the future risk of chronic kidney disease in offspring of obese mothers with and without type 2 diabetes

Chronic kidney disease (CKD) is a major health burden driven mostly by obesity and type 2 diabetes mellitus. 1/3 of diabetic patients are at risk of CKD progression for unknown reas more...

Supervisor(s): Saad, Sonia (Dr), Pollock, Carol (Professor)

Utilising Clinically Relevant Mechanisms to Develop Neuroprotective Strategies in Glaucoma

Neuroprotective strategies for glaucoma therapy have been investigated extensively over the last few years with disappointing clinical trial results. However a significant proportio more...

Supervisor(s): White, Andrew (Dr)

Conserved mechanisms of chronic pain

This project involves combining human genomics data for chronic pain disease with high throughput behavioral genomics techniques in fruit fly in order to better understand how chron more...

Supervisor(s): Neely, Greg (Professor)

Pharmacological targeting of the metastasis suppressor NDRG1 using novel therapeutics

Metastasis is the major killer in cancer, being extremely difficult to treat. This project will elucidate the molecular mechanisms that initiate and sustain metastatic progression, more...

Supervisor(s): Kovacevic, Zaklina (Dr), Richardson, Des (Professor)

How to stop an epileptic seizure - looking for the right molecules to target

Over 400 proteins are implicated in epilepsy. This project involves interrogating models of epilepsy to determine which are the key pathways and molecular mechanisms which could be more...

Supervisor(s): Graham, Mark (Dr)

Prevention of cardiac side effects of cancer treatment

This project will investigate a novel drug combination therapy that has potential benefits in cancer treatment induced heart failure by targeting Na+-K+ pump function. more...

Supervisor(s): Liu, Chia-chi (Dr), Ramussen, Helge (Professor)

NHMRC Translational Australian Clinical Toxicology (TACT) Program

A range of PhD research project opportunities in human toxicology exist within the TACT program. We are looking for talented and motivated doctoral candidates, with or without a pri more...

Supervisor(s): Buckley, Nicholas (Professor), Dawson, Andrew (Professor)

Telomere deprotection and cancer

Genome stability in human cells is maintained through the coordinated functions of the DNA damage response. We study these processes with particular interest in the pathways that re more...

Supervisor(s): Cesare, Tony (Dr)

Investigating the genomic diversity of the adaptive and innate immune systems in wild pigs and peccaries

This project focuses on elucidating the genetic diversity and differentiation of the adaptive and innate immune systems in wild pigs (Suidae) and peccaries (Tayassuidae)  more...

Supervisor(s): Gongora, Jaime (Associate Professor)

The Renin-Angiotensin System and its Role in Neuroprotective Strategies in a Glaucoma Model

At present, the only treatment for glaucoma is intraocular pressure control. We know some people still get worse despite good pressure control. We have evidence that a system previo more...

Supervisor(s): White, Andrew (Dr)