Your Search Results

Beyond Neuroinflammation: The Role of Microglia in Synaptic Plasticity

Microglia are the immune cells of the brain and are known to respond to infectious and non-infectious insults to the nervous system. Recently, a new function has been demonstrated f more...

Supervisor(s): Graeber, Manuel (Professor)

PET imaging of glioma in a TSPO knockout model

Glioblastoma is the most frequent primary brain tumour and the most malignant glial neoplasm (glioma) with predominantly astrocytic differentiation. Due to their invasive nature, gl more...

Supervisor(s): Graeber, Manuel (Professor), Banati, Richard (Professor)

How to stop an epileptic seizure - looking for the right molecules to target

Over 400 proteins are implicated in epilepsy. This project involves interrogating models of epilepsy to determine which are the key pathways and molecular mechanisms which could be more...

Supervisor(s): Graham, Mark (Dr)

How do molecules make memories? Understanding synaptic plasticity at the level of protein pathways and signalling.

This project aims to discover and validate new molecular mechanisms of how synaptic plasticity, which underlies learning and memory, is regulated by protein interactions and phospho more...

Supervisor(s): Graham, Mark (Dr)

Factors affecting oral health in cerebral palsy patients: dental caries experience, microbiome and oral health related quality of life (OHRQoL)

Cerebral palsy (CP) is a set of nonprogressive neuromuscular disorders caused by defects in the developing fetal brain. Children with Cerebral Palsy are often have physical, coordin more...

Supervisor(s): Akhter, Rahena (Dr)

The therapeutic potential of oxytocin in alcohol related harms

Alcohol is the most widely abused recreational drug in the world and arguably the most harmful. Acute alcohol intoxication can result in disability or death through alcohol related more...

Supervisor(s): McGregor, Iain (Professor)

Teaching dumb agents to play smart games in economics

Economic game theory is one of the most powerful but  surprisingly simple tools we have to understand many of the key aspects of social interactions. This has included the evol more...

Supervisor(s): Harre, Michael (Dr)

The Perceptual Expertise of Skilled Game Players: What can they see that I can’t

With the ability to store millions of records of decisions people have made and the context in which they were made, we are left the interesting problem that we still do not know wh more...

Supervisor(s): Harre, Michael (Dr)

Chemotherapy-induced neuropathic pain, fatigue, and cognitive impairments

Cancer and cancer treatments are associated with a wide range of side effects, including those of the nervous system. These present as neuropathic pain, fatigue, and cognitive impai more...

Supervisor(s): Johnston, Ian (Dr)

Whole genome CRISPR screening to define drug mechanism of action

This project will involve new whole genome CRISPR editing strategies, coupled with bioinformatics analysis, to identify the complete molecular mechanism of action for relevant human more...

Supervisor(s): Neely, Greg (Professor)