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Genetics of Healthy Ageing

By exploiting the vast genetic landscape of an outbred mouse population we aim to explore the molecular cause of a range of diseases that limit healthy ageing in humans. This includ more...

Supervisor(s): James, David (Professor)

Multi-omic responses to dietary change: insights from poultry

Diet is a crucial mechanism by which organisms interact with their environment. The body responds to the food it receives to control nutrient uptake and moderate physiological pathw more...

Supervisor(s): Grueber, Catherine (Dr), Liu, Sonia (Dr), Whittington, Camilla (Dr)

Curing antibiotic resistance plasmid from Enterobacteriaceae

The project includes to understand the biology of antibiotic resistance plasmids and develop effective strategy to cure them more...

Supervisor(s): Kamruzzaman, Muhammad (Dr), Iredell, Jon (Professor)

Clinical outcomes analysis of patients who undergo resection for malignant Hepato-Biliary tumours

Available projectsClinical and molecular markers of early tumour recurrence in patients with malignant hepato-biliary tumours,Clinical and molecular markers of metastatic potential more...

Supervisor(s): Hugh, Thomas J (Professor)

UNDERSTANDING GENETIC VARIATIONS IN BONE

Functional genomics is a field that is undergoing major changes in practice due to the accessibility of gene editing technologies. Our team has developed methods for gene editing in more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

GENE THERAPY FOR GENETIC BONE DISEASES

Gene therapy is becoming a practical approach to treat severe genetic conditions and in recent years conditions such as Spinal Muscular Atrophy (SMA) have been success stories. Our more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

Clinical outcomes analysis of patients who undergo resection of neuroendocrine liver metastases

The Upper GI surgery department at RNSH is a tertiary referral unit which has treated many patients with neuroendocrine tumours over the past 20 years. RNSH is recognized as a NSW c more...

Supervisor(s): Hugh, Thomas J (Professor)

Development of Tissue-Targeted Vectors for Musculoskeletal Gene Therapy

A unique opportunity is available for an outstanding PhD scholar to conduct research in developing tissue-targeted AAV vectors for gene delivery and CRISPR gene editing. more...

Supervisor(s): Schindeler, Aaron (Associate Professor)

Modulating coronary atherosclerosis through perivascular fat (PVAT)

Background: Organ-to-organ communications are vital for living systems and play critical roles in cellular homeostasis. Various studies have demonstrated the existence and significa more...

Supervisor(s): Misra, Ashish (Dr)

A Novel Role in Stabilizing Vulnerable Atherosclerotic Plaque

Atherosclerosis is the leading cause of cardiovascular deaths, accounting for ~30% of all deaths in Australia in 2018. Atherosclerotic plaque rupture leads to heart failure and stro more...

Supervisor(s): Misra, Ashish (Dr)