Experimental analysis of dry powder inhalers for pulmonary drug delivery

Summary

This project will apply state of the art experimental diagnostic techniques for the quantitative analysis of dry powder inhalers (DPIs). The project will focus on improving our fundamental understanding of dry powder flow processes using state-of-the-art laser diagnostic methods.

Supervisor(s)

Dr Agisilaos Kourmatzis

Research Location

Aerospace, Mechanical and Mechatronic Engineering

Program Type

PHD

Synopsis

Dry powder inhalers (DPIs) are a widely used mode of pulmonary drug delivery however their design is predominately based on trial and error analysis and in-vivo measurement outcomes. By designing a series of fundamental experiments we will be able to isolate the individual variables that are most responsible for the effectiveness of powder de-agglomeration and dispersion. The PhD student will design these experiments, develop the diagnostic techniques to take the appropriate measurements, and develop simple models to describe DPI behaviour. This project is an ongoing collaboration with the Faculty of Pharmacy.

Additional Information

This project is open to both domestic and international PhD students.  International students who do not have funding from their home country will be required to apply for a living allowance and tuition fee scholarships such as IPRS. Such scholarships are very competitive and a successful applicant would normally be within the top 5% of their graduating class. Correspondence with the supervisor should give evidence of these credentials.

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Keywords

Aerosols, drug delivery, fluid dynamics, sprays

Opportunity ID

The opportunity ID for this research opportunity is: 2282

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