Dysregulation of the inflammatory response in diabetes: Its role in poor wound healing
Summary
Diabetes is known to alter inflammatroy response but how this contributes to poor wound healing and other complications of diabetes is not known and will be investigated in this work.
Supervisor(s)
Dr Susan McLennan, Dr Nicholas Shackel
Research Location
Camperdown - School of Medical Sciences
Program Type
Masters/PHD
Synopsis
Studies in my laboratory investigate the effect of diabetes on inflammatory cell function. We have already shown that diabetes can alter the circulating monocyte and neutrophil phenotype but how this is related to the presence of diabetic complications in particular poor wound healing is not known.
Projects in this area would use a variety of techniques including but not limited to studies at the whole animal level, cell culture, flow cytometry and a variety of molecular and histological techniques.
Additional Information
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Keywords
diabetes, Wound healing, inflammation, miRNA, RNA, Imaging, Macrophage, neutrophil
Opportunity ID
The opportunity ID for this research opportunity is: 231
Other opportunities with Dr Susan McLennan
- Mechanism of the effect of diabetes on the inflammation and subsequent fibrosis
- Molecular studies of thyroid cancer and cutaneous squamous cell carcinoma
Other opportunities with Dr Nicholas Shackel