Biomolecular studies of Parkinson’s disease

Summary

Opportunities exist to join a leading group conducting research into Parkinson's disease. Our group combines the disciplines of biochemistry, immunology, molecular biology and cell biology to conduct cutting edge research aimed at understanding the causes of Parkinson's disease, developing novel therapeutics for its treatment, and identifying novel biomarkers for its earlier and more accurate detection.

Supervisor(s)

Dr Nicolas Dzamko

Research Location

Camperdown - Brain and Mind Centre

Program Type

PHD

Synopsis

Neurodegenerative diseases such as Parkinson's, Alzheimer's and other dementias contribute enormously to the global burden of disease. Our internationally recognised team conducts research into Parkinson's disease, a debilitating disorder with 20 people per day diagnosed in Australia alone. Project opportunities exist in a number of areas, ranging from clinical collaborations and translational research, through to disease modelling and discovery science. We employ a number of cutting edge techniques including induced pluripotent stem cell models of disease, Crispr-Cas9 mediated genome editing, mass spectrometry, preclinical modelling and machine learning. Other techniques routinely employed include, ELISA, flow cytometry, confocal microscopy, tissue culture, cell isolation, immunoblotting, sequencing and gene expression. With these skills, our graduates will be readily employable across many fields. Our research group is located at the multidisciplinary Brain and Mind Centre, providing an outstanding and supportive environment for students to work. The latest information on currently running projects is available at the supervisor Sydney Medical School profile page and potential applicants are encouraged to contact the supervisor with any questions.

Additional Information

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Keywords

biomarker, Neurodegeneration, Parkinson’s, inflammation, Induced Pluripotent Stem cells, cell biology. mutation, autophagy, Molecular, Biochemistry, disease modelling, drug discovery, dementia, immune, blood test.

Opportunity ID

The opportunity ID for this research opportunity is: 2514