Scaffolds for skeletal tissue regeneration

Summary

This project will modify calcium silicate ceramic scaffolds with divalent cations to improve their mechanical, osteoinductive and osteoconductive properties for bone regeneration.

Supervisor(s)

Professor Hala Zreiqat

Research Location

Aerospace, Mechanical and Mechatronic Engineering

Program Type

N/A

Synopsis

Bone defects are a great challenge to reconstructive surgery. As populations age and life expectancy increases, demand is growing for synthetic materials that can regenerate lost or diseased bone. In 2005, annual demand for bone graft substitutes exceeded 500,000 in the US and 2.2 million worldwide, and costs reached almost US$2.5 billion. We have developed novel 3D scaffolds with clinically relevant attributes for bone and vascular tissue ingrowth for treating large bone defects in load-bearing applications.

Keywords

Biomaterials, scaffolds, Bone, ceramics

Opportunity ID

The opportunity ID for this research opportunity is: 303

Other opportunities with Professor Hala Zreiqat

• Strategies for Building Bone
• Surface modification of biomaterials for orthopaedic applications
• Role of S100A8 and S100A9 in osteoarthritis