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What determines memory T cell responses following immunisation for tuberculosis?

This will provide excellent training in cellular immunisation and vaccine development against a major human pathogen more...

Supervisor(s): Britton, Warwick J (Professor)

Diseases of the Aorta

The causes of sporadic thoracic aortic aneurysms are not understood but the consequences of this disease can be catastrophic. We have developed an animal model of disease and this t more...

Supervisor(s): Gamble, Jennifer (Professor)

MicroRNAs in disease

Regulation of the endothelial cell barrier integrity is critical in inducing new blood vessel formation (angiogenesis), in developing an inflammatory response and importantly in res more...

Supervisor(s): Gamble, Jennifer (Professor)

Understanding the role of novel genes in disease

From mRNA arrays we have identified a number of ‘novel’ genes that influence tissue function. Our studies are investigating the biochemical basis for the mechanism of ac more...

Supervisor(s): Gamble, Jennifer (Professor)

Targeting melanoma secretory pathways.

Cancer cells secrete a variety of factors that induce tumour growth, metastasis, angiogenesis, and alter the tumour stroma to create a more favourable microenviroment. This project more...

Supervisor(s): Weninger , Wolfgang (Professor), Beaumont, Kimberley (Dr)

Cell cycle control of DNA repair in lymphoid cells

PhD opportunity in an NHMRC-funded group to determine how cell cycle determines the fidelity of DNA repair in activated B cells in vivo. more...

Supervisor(s): Jolly, Chris (Dr)

Control of complement cascade by labile disulphide bonds

The complement system is a key component of innate immunity that offers sophisticated protection against threats to the host organism. Complement is also an important component of t more...

Supervisor(s): Chiu, Joyce (Dr)

Control of immune cell activity via a redox switch in integrin

Our immune system protects us from invasion of pathogens and toxic materials. Immune cells such as monocytes and neutrophils circulate in the blood to monitor foreign materials and more...

Supervisor(s): Chiu, Joyce (Dr)

Imaging atherogenesis in a zebrafish model

This project will characterise immune cell dynamics during atherogenesis by live imaging, and investigate the importance of vascular remodelling and leakage in fuelling atheroma pat more...

Supervisor(s): Oehlers, Stefan (Dr), Britton, Warwick J (Professor)

Vascular dysfunction in mycobacterial pathogenesis

This project will investigate the importance of vascular remodelling and leakage in fuelling tuberculosis infection more...

Supervisor(s): Oehlers, Stefan (Dr), Britton, Warwick J (Professor)