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Structure-based drug design with Kynurenine Aminotransferase-2

Human kynurenine amino transferase-2 (KAT-2) forms the basis of a structure-based drug design study with implications for schizophrenia and gender differences.  The various asp more...

Supervisor(s): Church, W Bret (Dr)

Targeting Rab7 and TBC1D15 to overcome mitochondrial dysfunction in neurological diseases

Pharmacological manipulation of contacts between mitochondria and LE/Lys could provide opportunities to improve PD, CMT2B and NPC disease. Virtual screening of compound libraries wi more...

Supervisor(s): Grewal , Thomas (Associate Professor), Groundwater, Paul (Professor), Hibbs, David (Dai) (Professor)