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Determining the functional significance of non-coding DNA variants in genes for complex traits involving gene-environmental interactions

To identify non-protein coding DNA changes in genes that interact with the environment using 2 models – sporadic amyotrophic lateral sclerosis for the vulnerability to environ more...

Supervisor(s): Yu, Bing (Associate Professor)

The role of a novel mutant gene in dementia and motor neuron disease

We have identified a new gene that when mutated causes dementia and motor neuron disease (MND), diseases that are currently incurable. This project will examine how this mutated gen more...

Supervisor(s): Dobson-Stone, Carol (Dr)

Search for a cause: the role of astrocytes in the early pathology of Parkinson's disease

The projects in our lab are directed towards finding the cause of Parkinson’s Disease.  In particular we want to know what is the nature of the mechanism that sets the ne more...

Supervisor(s): Allbutt, Haydn (Dr)