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Maternal autoimmunity increases risk of neurodevelopmental problems in offspring.

Maternal autoimmunity is a recognised risk factor for autism and other neurodevelopmental and psychiatric disorders in the offspring. It is well established in humans and animal mod more...

Supervisor(s): Dale, Russell (Professor), Hofer, Markus (Dr)

The role of autoantibodies against neuronal receptors in immune-mediated neurological and psychiatric disorders.

The neuroimmunology group investigates the role of autoimmunity and inflammation of the brain resulting in neurological disturbance in children. Over the last 5-10 years there has b more...

Supervisor(s): Dale, Russell (Professor), Brilot-Turville, Fabienne (Dr)

Targeting Regulatory T Cells for the Treatment of Autoimmune Renal Disease

This project will investigate the role of regulatory T cells for the treatment of autoimmunity kidney disease.    more...

Supervisor(s): Alexander, Stephen (Professor), Wang, Yuan Min (Dr)

Cumulative modeling of Maternal Immune Activation to assess risk factors of common neurodevelopmental disease

Neurodevelopmental disorders such as epilepsy, autism, Tourette syndrome or ADHD affect 10% of children. There is increasing evidence that maternal inflammation whilst pregnant, ter more...

Supervisor(s): Hofer, Markus (Dr)

Defining the clinical and immunogenetic profile in antibody-associated demyelination

Masters or PhD opportunity ideally suited for a medical or neurology trainee or fellow with a commitment to building expertise in clinical and translational neuroimmunology. more...

Supervisor(s): Ramanathan, Sudarshini (Dr), Brilot-Turville, Fabienne (Dr), Dale, Russell (Professor)

Antibody-Mediated Pain Syndrome (AMPS)

Complex regional pain syndromes (CRPSs) are painful disorders with pathophysiological etiologies associated with neuroinflammation, peripheral nerve damage, central sensitization, more...

Supervisor(s): Parratt, John (Dr), Ng, Karl (Associate Professor)

Unravelling mechanisms determining the balance between tolerance and immunity in the liver

Role of primary T cell activation in the liver in CD8 T cell tolerance more...

Supervisor(s): Bertolino, Patrick (Dr)

Computational approaches to elucidate Multiple Sclerosis and Contact Dermatitis pathogenesis, and its treatment through ultraviolet light exposure

Allergies and autoimmunity are complex immune system aberrations. Both involve multiple immune cell populations coordinating across several organs of the body. The growing prevalenc more...

Supervisor(s): Read, Mark (Dr)

Regulatory T cells

Regulatory T cells (Tregs) control autoimmune, allergic and inflammatory responses, and are involved in organ transplantation and immune responses to cancer. more...

Supervisor(s): Fazekas, Barbara (Professor)