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Formulation and delivery of therapeutic phages to combat infections caused by multidrug-resistant bacteria

Antimicrobial resistance is one of the greatest threats to human health. Bacteriophage (phage) therapy has regained interest in recent years due to alarming spread of antibiotic res more...

Supervisor(s): Chan, Kim (Professor)

UNDERSTANDING GENETIC VARIATIONS IN BONE

Functional genomics is a field that is undergoing major changes in practice due to the accessibility of gene editing technologies. Our team has developed methods for gene editing in more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

GENE THERAPY FOR GENETIC BONE DISEASES

Gene therapy is becoming a practical approach to treat severe genetic conditions and in recent years conditions such as Spinal Muscular Atrophy (SMA) have been success stories. Our more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Munns, Craig (Associate Professor)

PRECLINICAL AND CLINICAL DEVELOPMENT OF NOVEL BONE-BINDING ANTIMICROBIALS

Our team has spent several years developing and testing new a new class of drugs termed bone-binding antimicrobials (BBAs). Our lead compound (BBA-1) has been shown to have antimicr more...

Supervisor(s): Schindeler, Aaron (Associate Professor), Little, David (Professor)

Development of Tissue-Targeted Vectors for Musculoskeletal Gene Therapy

A unique opportunity is available for an outstanding PhD scholar to conduct research in developing tissue-targeted AAV vectors for gene delivery and CRISPR gene editing. more...

Supervisor(s): Schindeler, Aaron (Associate Professor)