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Regulatory Proteins in Development and Disease

PhD projects in this laboratory are focused on understanding how key proteins can lead to both normal development and disease, and using this knowledge to develop reagents to inhibi more...

Supervisor(s): Matthews, Jacqueline (Professor)

Role of S100A8 and S100A9 in osteoarthritis

This projects involves the development of novel scaffolds and biomaterials for bone and cartilage regeneration. more...

Supervisor(s): Zreiqat, Hala (Professor)

Regulation of ion transport in the respiratory epithelium in health and disease

The project will focus on elucidating the mechanisms by which respiratory pathogens including influenza, parainfluenza, avian influenza (H5N1) viruses, and microbacterium tuberculos more...

Supervisor(s): Cook, David I (Professor)

Towards a cure for Type I diabetes mellitus

Transfect a lentivirus construct expressing an immunosuppressive peptide in islet cells for the treatment of diabetes type I more...

Supervisor(s): Manolios, Nicholas (Professor), Logan, Grant (Dr)

Regulatory T cells

Regulatory T cells (Tregs) control autoimmune, allergic and inflammatory responses, and are involved in organ transplantation and immune responses to cancer. more...

Supervisor(s): Fazekas, Barbara (Professor)

Implantable Medical Devices

The ability to attach functional proteins, antibodies and enzymes to surfaces underpins the development of the next generation of implantable medical devices, biosensors and protein more...

Supervisor(s): Bilek, Marcela (Professor)

THE USE OF MARIJUANA AND/OR ENDOCANNABINOID OILS FOR THE TREATMENT OF OSTEOARTHRITIS (OA)

Pre-clinical studies for the effects of CBD and analogues for the treatment of osteoarthritis more...

Supervisor(s): Manolios, Nicholas (Professor), Arnold, Jonathon (Associate Professor)

Strategies for Building Bone

This project will investigate the use of biological agents in stimulating bone growth and inhibiting bone resorption. more...

Supervisor(s): Zreiqat, Hala (Professor)

Surface modification of biomaterials for orthopaedic applications

This project will establish that our novel modified calcium silicate materials have enhanced bioactivity and osseointegration properties for coatings onto orthopaedic implants. more...

Supervisor(s): Zreiqat, Hala (Professor)

Scaffolds for skeletal tissue regeneration

This project will modify calcium silicate ceramic scaffolds with divalent cations to improve their mechanical, osteoinductive and osteoconductive properties for bone regeneration. more...

Supervisor(s): Zreiqat, Hala (Professor)