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GENES AND CELL-CELL INTERACTIONS IN CANCER PROGRESSION..

Oncogenes, tumour suppressor genes and cell-cell interactions in cancer: which are important in driving tumour progression and invasion in squamous cell carcinomas? more...

Supervisor(s): Lyons, Guy (Associate Professor)

Investigation of the role of microRNAs in cell differentiation

Investigating the role of microRNAs in the regulation of stem cell multipotency and differentiation. more...

Supervisor(s): Rasko, John (Professor)

Prevalence and impact of incorrect cancer research publications targeting the functions of human genes

This PhD project analyses the reliability of the cancer research literature, from which new cancer biomarkers and molecular targets are derived. more...

Supervisor(s): Byrne, Jennifer (Professor)

Medicinal Chemistry and Biology - Development of Novel Anti-Tumour Agents for Cancer Treatment

This project is involved in the exciting development of novel drugs for the treatment of cancer and other conditions. more...

Supervisor(s): Richardson, Des (Professor)

Investigating the links between telomerase and the DNA damage response in cancer cells

The ribonucleoprotein enzyme telomerase counteracts telomere shortening in a majority of cancers, allowing for unlimited cell division. Most normal cells do not express telomerase, more...

Supervisor(s): Bryan, Tracy (Professor)

How do gingipains recognise their host cell targets?

Porphyromonas gingivalis is a gram-negative, rod-shaped anaerobic pathogenic bacterium that found in the oral cavity. more...

Supervisor(s): Collyer, Charles (Associate Professor)

REGULATION OF GROWTH FACTOR SIGNALLING IN THE EYE AND ITS IMPLICATIONS FOR NORMAL LENS BIOLOGY AND PATHOLOGY.

Growth factors play an essential role in regulating lens cell behaviour in the eye. Diverse intracellular signalling pathways work in concert or oppose each other to promote and reg more...

Supervisor(s): Lovicu, Frank J. (Professor)

Understanding ageing of the endothelium

The investigations are focussed on identifying the biological and molecular changes that occur when endothelial cells undergo senescence (ageing) and the impact on disease such as d more...

Supervisor(s): Gamble, Jennifer (Professor)

Regulatory Proteins in Development and Disease

PhD projects in this laboratory are focused on understanding how key proteins can lead to both normal development and disease, and using this knowledge to develop reagents to inhibi more...

Supervisor(s): Matthews, Jacqueline (Professor)

Molecular Dynamics of Glutamate Transporters

The aim of this project is to develop a molecular model for the mechanism of glutamate transport and through this we expect to identify novel means of pharmacologically manipulating more...

Supervisor(s): Ryan, Renae (Associate Professor)